HitPredict

Interactor 1: YPEL5 (P62699)
Protein yippee-like 5
Gene: YPEL5

Interactor 2: RMD5A (Q9H871)
E3 ubiquitin-protein transferase RMND5A (EC 2.3.2.27) (P44CTLH) (Protein RMD5 homolog A)
Gene: RMND5A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.84	0.60	0.714

Property	Details
Experiments	26186194, 28514442, 27173435, 29911972, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000151 - ubiquitin ligase complex GO:0005634 - nucleus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 121 Hs			1 391
+	Hs
		977147 YPEL5_HUMAN (1-121): 4.58e-60: 182: 100.00		RMD5B_HUMAN (1-391): 2.21e-152: 437: 69.72
+	Hs
		977131 YPEL5_HUMAN (1-121): 4.58e-60: 182: 100.00		MAEA_HUMAN (25-390): 1.22e-111: 334: 20.05
+	Dm
		1489787 YIPP_DROME (1-112): 2.39e-53: 165: 75.89		Q9W2N5_DROME (58-391): 2.15e-116: 347: 45.75
+	Dm
		1321200 YIPP_DROME (1-112): 2.39e-53: 165: 75.89		Q8MSB1_DROME (1-390): 6.22e-103: 311: 23.21
+	Sc
		795674 MOH1_YEAST (14-108): 7.58e-40: 131: 40.00		RMD5_YEAST (10-391): 2.87e-90: 280: 24.22
+	Hs
		977165 YPEL5_HUMAN (1-121): 4.58e-60: 182: 100.00		GID8_HUMAN (114-280): 5.64e-39: 141: 17.54
+	Dm
		1488007 YIPP_DROME (1-112): 2.39e-53: 165: 75.89		Q9VWS1_DROME (114-281): 3.33e-34: 128: 17.75
+	Sc
		795668 MOH1_YEAST (14-108): 7.58e-40: 131: 40.00		FYV10_YEAST (23-390): 1.02e-39: 149: 14.09
+	Hs
		977151 YPEL5_HUMAN (1-121): 4.58e-60: 182: 100.00		RANB9_HUMAN (87-214): 3.63e-11: 66.7: 16.41