Protein: YPEL5
Protein yippee-like 5

Gene: YPEL5
Organism: Homo sapiens
Interactions: 86
UniProt ID: P62699

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0005576 - extracellular region
GO:0005634 - nucleus
GO:0005813 - centrosome
GO:0008283 - cell population proliferation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

977124

IKZF1
DNA-binding protein Ikaros

2

1

High-throughput

0.776

High

977136

ZN655
Zinc finger protein 655

2

0

High-throughput

0.742

High

977171

PLAL2
Zinc finger protein PLAGL2

2

0

High-throughput

0.742

High

977151

RANB9
Ran-binding protein 9

6

5

Small-scale

0.735

High

977162

RMD5A
E3 ubiquitin-protein transferase RMND5A

5

9

High-throughput

0.714

High

977132

ARMC8
Armadillo repeat-containing protein 8

4

1

High-throughput

0.691

High

567827

PRG2
Bone marrow proteoglycan

4

0

High-throughput

0.661

High

977130

RBP10
Ran-binding protein 10

3

5

Small-scale

0.656

High

977165

GID8
Glucose-induced degradation protein 8 homolog

3

12

High-throughput

0.650

High

977131

MAEA
E3 ubiquitin-protein transferase MAEA

3

12

High-throughput

0.646

High

977161

WDR26
WD repeat-containing protein 26

2

4

High-throughput

0.611

High

136677

TRAF5
TNF receptor-associated factor 5

2

1

High-throughput

0.606

High

192365

GSC2
Homeobox protein goosecoid-2

2

3

High-throughput

0.606

High

246231

MABP1
Mitogen-activated protein kinase-binding protein 1

2

2

High-throughput

0.606

High

977125

IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon

1

0

Small-scale

0.586

High

977122

TIF1B
Transcription intermediary factor 1-beta

2

1

Small-scale

0.584

High

680838

PSA1
Proteasome subunit alpha type-1

2

0

High-throughput

0.580

High

977153

PFD5
Prefoldin subunit 5

2

0

High-throughput

0.580

High

977157

CTDS1
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1

2

0

High-throughput

0.580

High

377281

GLUC
Pro-glucagon [Cleaved into: Glicentin; Glicentin-related polypeptide

2

0

High-throughput

0.576

High

652639

GNLY
Granulysin

2

0

High-throughput

0.576

High

977164

EMIL3
EMILIN-3

2

0

High-throughput

0.576

High

977138

SHC3
SHC-transforming protein 3

2

1

High-throughput

0.553

High

615175

PACA
Pituitary adenylate cyclase-activating polypeptide

2

0

High-throughput

0.547

High

977147

RMD5B
E3 ubiquitin-protein transferase RMND5B

1

9

High-throughput

0.536

High

903011

NOVA1
RNA-binding protein Nova-1

1

0

Small-scale

0.529

High

977141

CSN5
COP9 signalosome complex subunit 5

1

0

Small-scale

0.529

High

977133

M4K3
Mitogen-activated protein kinase kinase kinase kinase 3

1

0

High-throughput

0.517

High

169297

LECT2
Leukocyte cell-derived chemotaxin-2

1

0

High-throughput

0.513

High

250537

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

0

High-throughput

0.513

High

270237

MTG16
Protein CBFA2T3

1

0

High-throughput

0.513

High

477332

NMB
Neuromedin-B [Cleaved into: Neuromedin-B-32; Neuromedin-B]

1

0

High-throughput

0.513

High

528672

PPGB
Lysosomal protective protein

1

0

High-throughput

0.513

High

593656

BGAL
Beta-galactosidase

1

0

High-throughput

0.513

High

608532

DDX5
Probable ATP-dependent RNA helicase DDX5

1

0

High-throughput

0.513

High

649279

H1T
Histone H1t

1

0

High-throughput

0.513

High

872163

SOX2
Transcription factor SOX-2

1

0

High-throughput

0.513

High

977154

GDF15
Growth/differentiation factor 15

1

0

High-throughput

0.513

High

977156

WN10A
Protein Wnt-10a

1

0

High-throughput

0.513

High

977166

ATS1
A disintegrin and metalloproteinase with thrombospondin motifs 1

1

0

High-throughput

0.513

High

977140

COR2A
Coronin-2A

1

1

High-throughput

0.489

High

977149

JPH4
Junctophilin-4

1

1

High-throughput

0.489

High

977175

FBX7
F-box only protein 7

1

0

High-throughput

0.480

High

315398

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.479

High

970253

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

1

High-throughput

0.479

High

977169

MKLN1
Muskelin

1

1

High-throughput

0.479

High

561353

TDGF1
Protein Cripto

1

0

High-throughput

0.458

High

814915

GDNF
Glial cell line-derived neurotrophic factor

1

0

High-throughput

0.458

High

955908

RAB8A
Ras-related protein Rab-8A

1

0

High-throughput

0.458

High

977119

H31
Histone H3.1

1

0

High-throughput

0.458

High

977121

GPS2
G protein pathway suppressor 2

1

0

High-throughput

0.458

High

977139

ESR2
Estrogen receptor beta

1

0

High-throughput

0.458

High

977160

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

977170

FZR1
Fizzy-related protein homolog

1

0

High-throughput

0.458

High

977120

TLE1
Transducin-like enhancer protein 1

1

2

High-throughput

0.445

High

977126

EMAL3
Echinoderm microtubule-associated protein-like 3

1

2

High-throughput

0.445

High

977123

CTBP1
C-terminal-binding protein 1

1

0

High-throughput

0.426

High

977135

LYPD1
Ly6/PLAUR domain-containing protein 1

1

0

High-throughput

0.426

High

977167

TCAL9
Transcription elongation factor A protein-like 9

1

0

High-throughput

0.426

High

977176

INSL6
Insulin-like peptide INSL6

1

0

High-throughput

0.426

High

977172

COR2B
Coronin-2B

1

1

High-throughput

0.407

High

409569

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

2

0

High-throughput

0.318

High

977144

DDT4L
DNA damage-inducible transcript 4-like protein

2

0

High-throughput

0.316

High

977158

RM18
Large ribosomal subunit protein uL18m

2

0

High-throughput

0.313

High

977146

CNRP1
CB1 cannabinoid receptor-interacting protein 1

1

0

Small-scale

0.288

High

717059

ECHM
Enoyl-CoA hydratase, mitochondrial

1

0

High-throughput

0.279

Low

977128

EFHC2
EF-hand domain-containing family member C2

1

0

High-throughput

0.279

Low

977129

STYL2
Serine/threonine/tyrosine-interacting-like protein 2

1

0

High-throughput

0.279

Low

977137

KCTD6
BTB/POZ domain-containing protein KCTD6

1

0

High-throughput

0.279

Low

977159

WDCP
WD repeat and coiled-coil-containing protein

1

0

High-throughput

0.279

Low

977163

E41L5
Band 4.1-like protein 5

1

0

High-throughput

0.279

Low

293510

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.249

Low

947125

NLRP6
NACHT, LRR and PYD domains-containing protein 6

1

0

High-throughput

0.249

Low

977134

AMOL1
Angiomotin-like protein 1

1

0

High-throughput

0.249

Low

977145

RT24
Small ribosomal subunit protein uS3m

1

0

High-throughput

0.249

Low

977155

RM04
Large ribosomal subunit protein uL4m

1

0

High-throughput

0.249

Low

977173

RT28
Small ribosomal subunit protein bS1m

1

0

High-throughput

0.249

Low

977174

RT02
Small ribosomal subunit protein uS2m

1

0

High-throughput

0.249

Low

871917

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

1

0

High-throughput

0.232

Low

977127

ASTRB
Protein Aster-B

1

0

High-throughput

0.232

Low

977142

PIGT
GPI-anchor transamidase component PIGT

1

0

High-throughput

0.232

Low

977143

SH3K1
SH3 domain-containing kinase-binding protein 1

1

0

High-throughput

0.232

Low

977148

CC120
Coiled-coil domain-containing protein 120

1

0

High-throughput

0.232

Low

977150

PEO1
Twinkle mtDNA helicase

1

0

High-throughput

0.232

Low

977152

HPLN3
Hyaluronan and proteoglycan link protein 3

1

0

High-throughput

0.232

Low

977168

MRM2
rRNA methyltransferase 2, mitochondrial

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025