HitPredict

Interactor 1: SYF1 (Q04048)
Pre-mRNA-splicing factor SYF1 (PRP19-associated complex protein 90) (Synthetic lethal with CDC40 protein 1)
Gene: SYF1

Interactor 2: SP382 (Q06411)
Pre-mRNA-splicing factor SPP382 (CLF1 complex factor 8) (Nineteen complex-related protein 1) (NTC-related protein 1) (Suppressor of PRP38 protein 2)
Gene: SPP382

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	16357217, 14690591
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000349 - generation of catalytic spliceosome for first transesterification step GO:0005634 - nucleus GO:0071008 - U2-type post-mRNA release spliceosomal complex
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 859 Sc			1 708
+	Sc
		982879 RRP5_YEAST (572-839): 8.35e-22: 104: 15.96		SP382_YEAST (1-708): 0: 1505: 100.00
+	Sc
		586444 PRP6_YEAST (157-799): 5.81e-22: 103: 12.19		SP382_YEAST (1-708): 0: 1505: 100.00
+	Sc
		987205 CLF1_YEAST (4-377): 2.18e-12: 72.7: 11.71		SP382_YEAST (1-708): 0: 1505: 100.00