HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	27248496, 30804502, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0032991 - protein-containing complex GO:0070062 - extracellular exosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 2115
+	Hs
		176961 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		CE290_HUMAN (257-2069): 1.44e-48: 194: 12.21
+	Hs
		776796 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		MYH11_HUMAN (1100-2059): 2.82e-37: 157: 10.94
+	Hs
		563047 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		MYH8_HUMAN (1083-2115): 4.32e-37: 156: 10.06
+	Hs
		772717 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		MYH9_HUMAN (1033-1891): 1.2e-33: 145: 10.62
+	Hs
		773150 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		MYH10_HUMAN (1257-2089): 8.04e-33: 142: 11.87
+	Hs
		883885 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		CENPF_HUMAN (1-781): 2.3e-32: 141: 12.77
+	Hs
		980254 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		CP250_HUMAN (1160-2114): 1.32e-28: 128: 11.27
+	Hs
		535928 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		MYH3_HUMAN (930-1731): 1.32e-24: 115: 12.39
+	Hs
		979690 H4_HUMAN (1-103): 1.39e-48: 151: 100.00		EEA1_HUMAN (70-766): 2.58e-24: 114: 15.40
+	Sc
		381898 H4_YEAST (18-103): 6.16e-41: 132: 90.70		USO1_YEAST (867-1693): 9.84e-11: 69.7: 18.63