HitPredict

Interactor 1: UB2D2 (P62837)
Ubiquitin-conjugating enzyme E2 D2 (EC 2.3.2.23) ((E3-independent) E2 ubiquitin-conjugating enzyme D2) (EC 2.3.2.24) (E2 ubiquitin-conjugating enzyme D2) (Ubiquitin carrier protein D2) (Ubiquitin-conjugating enzyme E2(17)KB 2) (Ubiquitin-conjugating enzyme E2-17 kDa 2) (Ubiquitin-protein ligase D2) (p53-regulated ubiquitin-conjugating enzyme 1)
Gene: UBE2D2

Interactor 2: RS27A (P62979)
Ubiquitin-ribosomal protein eS31 fusion protein (Ubiquitin carboxyl extension protein 80) [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31 (40S ribosomal protein S27a)]
Gene: RPS27A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	38334954
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~ubiquitin
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0016567 - protein ubiquitination GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 147 Hs			1 156
+	Hs
		957057 UB2D3_HUMAN (1-147): 2.22e-81: 237: 97.28		RS27A_HUMAN (1-156): 3.57e-76: 225: 100.00
+	Hs
		73732 UB2E3_HUMAN (4-146): 5.71e-74: 221: 66.43		B2RDW1_HUMAN (1-156): 3.57e-76: 225: 100.00
+	Hs
		982163 UB2D2_HUMAN (1-147): 1.58e-82: 240: 100.00		RL40_HUMAN (1-125): 5.35e-44: 142: 64.80
+	Hs
		957058 UB2D3_HUMAN (1-147): 2.22e-81: 237: 97.28		RL40_HUMAN (1-125): 5.35e-44: 142: 64.80
+	Rn
		92896 UB2D1_RAT (1-147): 1.1e-82: 241: 89.12		UBC_RAT (1-119): 1.58e-36: 134: 68.29
+	Mm
		509006 UB2D3_MOUSE (1-147): 2.22e-81: 237: 97.28		UBC_MOUSE (1-119): 1.08e-36: 135: 67.48
+	At
		1167874 UBC28_ARATH (1-147): 3.56e-83: 242: 80.27		UBQ3_ARATH (1-77): 2.2e-35: 126: 94.81
+	Hs
		507431 UB2D4_HUMAN (1-147): 3.4e-83: 242: 93.20		UBB_HUMAN (1-76): 6.68e-36: 125: 100.00
+	Dm
		683066 UBCD1_DROME (1-147): 4.19e-82: 239: 94.56		Q9W418_DROME (1-77): 1.7e-34: 127: 100.00
+	At
		762746 UBC8_ARATH (1-147): 1.51e-82: 240: 80.27		UBQ3_ARATH (1-77): 2.2e-35: 126: 94.81
+	Hs
		507147 UB2D2_HUMAN (1-147): 1.58e-82: 240: 100.00		UBB_HUMAN (1-76): 6.68e-36: 125: 100.00
+	At
		762762 UBC9_ARATH (1-147): 4.78e-82: 239: 80.27		UBQ3_ARATH (1-77): 2.2e-35: 126: 94.81
+	At
		762777 UBC10_ARATH (1-147): 4.68e-82: 239: 79.59		UBQ3_ARATH (1-77): 2.2e-35: 126: 94.81
+	At
		762787 UBC11_ARATH (1-147): 2.8e-82: 239: 79.59		UBQ3_ARATH (1-77): 2.2e-35: 126: 94.81
+	Hs
		507136 UB2D3_HUMAN (1-147): 2.22e-81: 237: 97.28		UBB_HUMAN (1-76): 6.68e-36: 125: 100.00
+	Hs
		1217033 UB2E3_HUMAN (4-146): 5.71e-74: 221: 66.43		Q5U5U6_HUMAN (1-76): 6.68e-36: 125: 100.00
+	Hs
		507301 UB2E3_HUMAN (4-146): 5.71e-74: 221: 66.43		UBB_HUMAN (1-76): 6.68e-36: 125: 100.00
+	At
		842109 UBC2_ARATH (2-144): 5.86e-70: 209: 46.85		UBQ3_ARATH (1-77): 2.2e-35: 126: 94.81
+	Hs
		507116 UBE2A_HUMAN (2-144): 3.28e-70: 209: 39.16		UBB_HUMAN (1-76): 6.68e-36: 125: 100.00
+	At
		683037 UBC1_ARATH (2-144): 7.88e-70: 208: 46.85		UBQ3_ARATH (1-77): 2.2e-35: 126: 94.81