HitPredict

Interactor 1: UBB (P0CG47)
Polyubiquitin-B [Cleaved into: Ubiquitin]
Gene: UBB

Interactor 2: UBE2A (P49459)
Ubiquitin-conjugating enzyme E2 A (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme A) (RAD6 homolog A) (HR6A) (hHR6A) (Ubiquitin carrier protein A) (Ubiquitin-protein ligase A)
Gene: UBE2A

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	24981860
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~ubiquitin
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 229 Hs			1 152
+	Hs
		507431 UBB_HUMAN (1-229): 2.65e-99: 289: 100.00		UB2D4_HUMAN (5-149): 3.34e-79: 232: 40.69
+	Hs
		507147 UBB_HUMAN (1-229): 2.65e-99: 289: 100.00		UB2D2_HUMAN (5-149): 2.43e-78: 230: 38.62
+	Hs
		508868 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		UB2D4_HUMAN (5-149): 3.34e-79: 232: 40.69
+	Hs
		507136 UBB_HUMAN (1-229): 2.65e-99: 289: 100.00		UB2D3_HUMAN (5-149): 5.84e-77: 226: 38.62
+	Hs
		507701 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		UB2D1_HUMAN (5-149): 1.64e-78: 230: 40.00
+	Hs
		507793 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		UB2D2_HUMAN (5-149): 2.43e-78: 230: 38.62
+	Xl
		982387 Q7SY79_XENLA (1-228): 1.28e-92: 285: 100.00		UB2D2_XENLA (5-149): 2.43e-78: 230: 38.62
+	Dm
		683066 Q9W418_DROME (1-228): 1.41e-93: 285: 100.00		UBCD1_DROME (5-149): 8.86e-78: 228: 38.62
+	Hs
		507755 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		UB2D3_HUMAN (5-149): 5.84e-77: 226: 38.62
+	At
		762746 UBQ3_ARATH (1-228): 1.09e-94: 281: 96.05		UBC8_ARATH (5-149): 1.97e-78: 230: 40.69
+	Hs
		507680 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		UBE2A_HUMAN (1-152): 2.23e-76: 225: 100.00
+	At
		762762 UBQ3_ARATH (1-228): 1.09e-94: 281: 96.05		UBC9_ARATH (5-149): 4.59e-78: 229: 41.38
+	At
		762777 UBQ3_ARATH (1-228): 1.09e-94: 281: 96.05		UBC10_ARATH (5-149): 4.44e-78: 229: 41.38
+	Hs
		1217033 Q5U5U6_HUMAN (1-229): 2.65e-99: 289: 100.00		UB2E3_HUMAN (3-150): 9.62e-73: 218: 35.14
+	Hs
		507301 UBB_HUMAN (1-229): 2.65e-99: 289: 100.00		UB2E3_HUMAN (3-150): 9.62e-73: 218: 35.14
+	Hs
		507805 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		UBE2B_HUMAN (1-151): 2.1e-74: 220: 96.03
+	Hs
		508456 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		UB2E2_HUMAN (3-150): 3.02e-73: 219: 35.14
+	Hs
		508388 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		UB2E3_HUMAN (3-150): 9.62e-73: 218: 35.14
+	At
		683037 UBQ3_ARATH (1-228): 1.09e-94: 281: 96.05		UBC1_ARATH (1-150): 6.95e-74: 219: 76.67
+	Hs
		507705 UBC_HUMAN (1-228): 7.54e-92: 285: 100.00		UB2E1_HUMAN (3-150): 2.46e-71: 214: 36.49