HitPredict

Interactor 1: MAD1 (Q05195)
Max dimerization protein 1 (Max dimerizer 1) (Protein MAD)
Gene: MXD1

Interactor 2: SMC3 (Q9UQE7)
Structural maintenance of chromosomes protein 3 (SMC protein 3) (SMC-3) (Basement membrane-associated chondroitin proteoglycan) (Bamacan) (Chondroitin sulfate proteoglycan 6) (Chromosome-associated polypeptide) (hCAP)
Gene: SMC3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.527

Property	Details
Experiments	9528857
Identification Methods	two hybrid, pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 221 Hs			1 1217
+	Hs
		840228 MXI1_HUMAN (7-207): 1.24e-66: 206: 58.53		SMC3_HUMAN (1-1217): 1.81e-124: 415: 100.00
+	Hs
		1055889 MAD4_HUMAN (11-201): 3.21e-61: 192: 52.82		SMC3_HUMAN (1-1217): 1.81e-124: 415: 100.00
+	Hs
		1314327 MAD3_HUMAN (8-191): 4.69e-53: 171: 45.88		SMC3_HUMAN (1-1217): 1.81e-124: 415: 100.00
+	Hs
		348261 MYC_HUMAN (39-139): 6.1e-32: 122: 22.77		SMC3_HUMAN (1-1217): 1.81e-124: 415: 100.00
+	Hs
		348010 MYC_HUMAN (39-139): 6.1e-32: 122: 22.77		SMC4_HUMAN (1-1206): 4.2e-80: 290: 16.85
+	Hs
		379920 MYCN_HUMAN (31-137): 2.13e-31: 121: 22.94		SMC4_HUMAN (1-1206): 4.2e-80: 290: 16.85
+	Hs
		346792 MYC_HUMAN (39-139): 6.1e-32: 122: 22.77		SMC1A_HUMAN (2-1211): 5.21e-79: 286: 16.36
+	Hs
		311454 MYC_HUMAN (39-139): 6.1e-32: 122: 22.77		SMC2_HUMAN (1-1217): 1.65e-73: 269: 19.14
+	Hs
		379626 MYCN_HUMAN (31-137): 2.13e-31: 121: 22.94		SMC1B_HUMAN (2-1217): 1.26e-73: 270: 14.06
+	Hs
		311457 MYCN_HUMAN (31-137): 2.13e-31: 121: 22.94		SMC2_HUMAN (1-1217): 1.65e-73: 269: 19.14