HitPredict

Interactor 1: DCE2 (Q05329)
Glutamate decarboxylase 2 (EC 4.1.1.15) (65 kDa glutamic acid decarboxylase) (GAD-65) (Glutamate decarboxylase 65 kDa isoform)
Gene: GAD2

Interactor 2: DCE2 (Q05329)
Glutamate decarboxylase 2 (EC 4.1.1.15) (65 kDa glutamic acid decarboxylase) (GAD-65) (Glutamate decarboxylase 65 kDa isoform)
Gene: GAD2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 17384644
Identification Methods x-ray crystallography
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Pyridoxal_deC~Pyridoxal_deC
Common GO terms GO:0000139 - Golgi membrane
GO:0004351 - glutamate decarboxylase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
and 20 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 585
Hs

1 585
+ Rn
+ Hs
+ Rn
+ Hs
+ Hs
+ At
+ Ce
+ Ce
+ Hs
+ At
+ Ec
+ Sc
+ Hs
+ Ec
+ Ec
+ Ec

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024