HitPredict

Interactor 1: UBIQP (P62972)
Polyubiquitin [Cleaved into: Ubiquitin]
Gene: UBIQP

Interactor 2: CHFR (Q5FWP4)
E3 ubiquitin-protein ligase CHFR (EC 2.3.2.27) (Checkpoint with forkhead and RING finger domains protein) (RING-type E3 ubiquitin transferase CHFR)
Gene: CHFR

Species: Xenopus laevis

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	18504434
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ubiquitin~zf-RING_2
Common GO terms	GO:0005634 - nucleus
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 167 Xl			1 625
+	Xl
		1204457 Q7SY79_XENLA (1-92): 1.09e-32: 123: 98.91		CHFR_XENLA (1-625): 0: 831: 100.00
+	Hs
		507598 UBC_HUMAN (16-167): 5.2e-60: 198: 100.00		BMI1_HUMAN (249-420): 8.39e-41: 153: 17.33
+	Hs
		508307 UBC_HUMAN (16-167): 5.2e-60: 198: 100.00		COP1_HUMAN (180-462): 2.23e-33: 138: 13.78
+	Hs
		507599 UBC_HUMAN (16-167): 5.2e-60: 198: 100.00		PCGF2_HUMAN (249-420): 1.16e-34: 136: 16.18
+	Hs
		507869 UBC_HUMAN (16-167): 5.2e-60: 198: 100.00		RING1_HUMAN (241-434): 1.57e-33: 134: 18.69
+	Hs
		508695 UBC_HUMAN (16-167): 5.2e-60: 198: 100.00		TOPRS_HUMAN (174-429): 5.06e-32: 134: 12.50
+	Hs
		508492 UBC_HUMAN (16-167): 5.2e-60: 198: 100.00		RING2_HUMAN (241-436): 2.14e-30: 123: 16.50
+	Hs
		302342 UBC_HUMAN (16-167): 5.2e-60: 198: 100.00		RNF8_HUMAN (258-347): 1e-25: 113: 27.78
+	Mm
		509143 UBC_MOUSE (1-120): 3.61e-40: 145: 94.17		TOPRS_MOUSE (221-429): 3.96e-36: 147: 15.67