HitPredict

Interactor 1: FGFR1 (P11362)
Fibroblast growth factor receptor 1 (FGFR-1) (EC 2.7.10.1) (Basic fibroblast growth factor receptor 1) (BFGFR) (bFGF-R-1) (Fms-like tyrosine kinase 2) (FLT-2) (N-sam) (Proto-oncogene c-Fgr) (CD antigen CD331)
Gene: FGFR1

Interactor 2: CALX (P27824)
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
Gene: CANX

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	18022941, 35384245
Identification Methods	affinity chromatography technology, proximity labelling technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 822 Hs			1 592
+	Hs
		601462 FGFR2_HUMAN (1-821): 0: 803: 71.21		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		161008 FGFR1_HUMAN (1-822): 0: 861: 100.00		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		607885 FGFR4_HUMAN (29-808): 0: 664: 55.60		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		654090 EPHA3_HUMAN (3-775): 0: 643: 19.03		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		654091 EPHA8_HUMAN (3-819): 0: 603: 19.35		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		654370 NTRK3_HUMAN (163-762): 3.3e-161: 491: 25.08		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		654101 UFO_HUMAN (8-815): 1.07e-155: 479: 21.98		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		384315 NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		161071 NTRK3_HUMAN (163-762): 3.3e-161: 491: 25.08		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		434139 RET_HUMAN (384-774): 2.63e-98: 332: 45.77		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		160995 NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		654124 FLT3_HUMAN (462-754): 8.76e-79: 276: 43.47		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		161002 RET_HUMAN (384-774): 2.63e-98: 332: 45.77		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		161031 FLT3_HUMAN (462-754): 8.76e-79: 276: 43.47		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		653493 UFO_HUMAN (8-815): 1.07e-155: 479: 21.98		CALR_HUMAN (67-470): 1.19e-141: 418: 38.33
+	Hs
		654302 PTK7_HUMAN (162-385): 7.97e-17: 87.5: 17.39		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		654121 VGFR3_HUMAN (31-128): 2.94e-10: 66.3: 21.15		CALX_HUMAN (1-592): 0: 786: 100.00
+	Hs
		384313 NTRK1_HUMAN (122-769): 8.92e-140: 434: 25.96		CALR_HUMAN (67-470): 1.19e-141: 418: 38.33
+	Hs
		161030 VGFR3_HUMAN (31-128): 2.94e-10: 66.3: 21.15		CLGN_HUMAN (11-546): 0: 652: 59.85
+	Hs
		653500 VGFR3_HUMAN (31-128): 2.94e-10: 66.3: 21.15		CALR_HUMAN (67-470): 1.19e-141: 418: 38.33