HitPredict

Interactor 1: TYRO3 (Q06418)
Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)
Gene: TYRO3

Interactor 2: DHB12 (Q53GQ0)
Very-long-chain 3-oxoacyl-CoA reductase (EC 1.1.1.330) (17-beta-hydroxysteroid dehydrogenase 12) (17-beta-HSD 12) (3-ketoacyl-CoA reductase) (KAR) (Estradiol 17-beta-dehydrogenase 12) (EC 1.1.1.62) (Short chain dehydrogenase/reductase family 12C member 1)
Gene: HSD17B12

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.500

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 890 Hs			1 312
+	Rn
		88679 INSR_RAT (232-788): 7.04e-127: 416: 27.65		D3ZPU3_RAT (1-312): 4.67e-89: 270: 78.85
+	Rn
		544934 INSR_RAT (232-788): 7.04e-127: 416: 27.65		PECR_RAT (38-300): 2.51e-71: 224: 19.33
+	Hs
		441517 MET_HUMAN (495-790): 3.89e-65: 240: 41.67		DHB12_HUMAN (1-312): 4.67e-98: 292: 100.00
+	Hs
		435661 IGF1R_HUMAN (333-779): 3.39e-61: 228: 32.53		DHB12_HUMAN (1-312): 4.67e-98: 292: 100.00
+	Hs
		609330 FGFR3_HUMAN (7-315): 1.59e-17: 89.8: 14.60		DHB12_HUMAN (1-312): 4.67e-98: 292: 100.00
+	Hs
		674449 UFO_HUMAN (6-344): 1.91e-14: 79.8: 14.56		DHB12_HUMAN (1-312): 4.67e-98: 292: 100.00
+	Hs
		1018331 MERTK_HUMAN (6-315): 1.52e-12: 73.6: 15.71		DHB12_HUMAN (1-312): 4.67e-98: 292: 100.00