HitPredict

Interactor 1: UBP2 (O75604)
Ubiquitin carboxyl-terminal hydrolase 2 (EC 3.4.19.12) (41 kDa ubiquitin-specific protease) (Deubiquitinating enzyme 2) (Ubiquitin thioesterase 2) (Ubiquitin-specific-processing protease 2)
Gene: USP2

Interactor 2: Q5U5U6 (Q5U5U6)
Epididymis secretory protein Li 50 (Ubiquitin B)
Gene: UBB

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.80	0.579

Property	Details
Experiments	16905103
Identification Methods	enzymatic study
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	UCH~ubiquitin
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 605 Hs			1 229
+	Hs
		288338 UBP2_HUMAN (1-605): 0: 634: 100.00		UBC_HUMAN (1-228): 7.54e-92: 285: 100.00
+	Rn
		1216904 UBP2_RAT (1-605): 0: 615: 89.16		UBC_RAT (1-181): 3.75e-62: 209: 96.13
+	Hs
		507635 UBP8_HUMAN (159-602): 5.88e-125: 396: 34.00		UBC_HUMAN (1-228): 7.54e-92: 285: 100.00
+	Hs
		508807 UBP21_HUMAN (72-604): 1.37e-127: 388: 35.15		UBC_HUMAN (1-228): 7.54e-92: 285: 100.00
+	Hs
		508843 UBP22_HUMAN (232-599): 3.57e-111: 344: 30.37		UBC_HUMAN (1-228): 7.54e-92: 285: 100.00
+	At
		1168007 UBP15_ARATH (84-604): 1.2e-106: 344: 20.95		UBQ3_ARATH (1-228): 1.09e-94: 281: 96.05
+	Hs
		67123 UBP27_HUMAN (197-599): 5e-109: 336: 27.96		UBC_HUMAN (1-228): 7.54e-92: 285: 100.00
+	Hs
		508751 UBP36_HUMAN (162-598): 1.94e-101: 334: 26.70		UBC_HUMAN (1-228): 7.54e-92: 285: 100.00
+	Hs
		508156 U17L2_HUMAN (201-604): 3.42e-106: 332: 25.61		UBC_HUMAN (1-228): 7.54e-92: 285: 100.00
+	Mm
		509134 UBP8_MOUSE (82-602): 4.11e-128: 404: 28.86		UBC_MOUSE (1-181): 8.42e-63: 209: 96.13
+	Hs
		507144 UBP46_HUMAN (243-600): 5.83e-105: 323: 24.33		UBB_HUMAN (1-229): 2.65e-99: 289: 100.00
+	Hs
		507979 UBP10_HUMAN (62-600): 2.12e-101: 327: 19.70		UBC_HUMAN (1-228): 7.54e-92: 285: 100.00
+	Hs
		508652 UBP42_HUMAN (189-599): 9.8e-98: 326: 26.07		UBC_HUMAN (1-228): 7.54e-92: 285: 100.00
+	Sc
		509565 UBP5_YEAST (69-598): 7.07e-102: 328: 22.58		UBI4P_YEAST (1-228): 3.4e-91: 274: 96.05
+	Mm
		509208 UBP3_MOUSE (231-602): 5.32e-106: 331: 33.08		UBC_MOUSE (1-181): 8.42e-63: 209: 96.13
+	Mm
		509277 UBP12_MOUSE (243-600): 5.02e-106: 325: 25.94		UBC_MOUSE (1-181): 8.42e-63: 209: 96.13
+	Mm
		509010 UBP46_MOUSE (243-600): 5.83e-105: 323: 24.33		UBC_MOUSE (1-181): 8.42e-63: 209: 96.13
+	At
		1300626 UBP15_ARATH (84-604): 1.2e-106: 344: 20.95		UBQ10_ARATH (1-153): 2.31e-54: 182: 95.43
+	Dm
		509811 NOT_DROME (228-598): 1.52e-107: 334: 30.34		UBIQP_DROME (1-154): 1.05e-53: 185: 99.35
+	Hs
		987252 UBP36_HUMAN (162-598): 1.94e-101: 334: 26.70		RS27A_HUMAN (153-228): 1.77e-44: 147: 100.00