HitPredict

Interactor 1: GRB2 (P62993)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2

Interactor 2: MYO1A (Q9UBC5)
Unconventional myosin-Ia (Brush border myosin I) (BBM-I) (BBMI) (Myosin I heavy chain) (MIHC)
Gene: MYO1A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	12577067
Identification Methods	pull down
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 217 Hs			1 1043
+	Hs
		227846 GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00		MYO1B_HUMAN (3-1042): 0: 1059: 50.22
+	Hs
		123655 GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00		MYO1C_HUMAN (5-1043): 0: 1043: 41.68
+	Hs
		773152 GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00		MYH10_HUMAN (10-998): 0: 1029: 29.28
+	Hs
		227764 LCK_HUMAN (3-202): 7.98e-34: 128: 28.44		MYO1B_HUMAN (3-1042): 0: 1059: 50.22
+	Hs
		123556 LCK_HUMAN (3-202): 7.98e-34: 128: 28.44		MYO1C_HUMAN (5-1043): 0: 1043: 41.68
+	Hs
		440259 LCK_HUMAN (3-202): 7.98e-34: 128: 28.44		MYO5A_HUMAN (1-1017): 0: 999: 29.28
+	Hs
		318239 LCK_HUMAN (3-202): 7.98e-34: 128: 28.44		MYO1D_HUMAN (7-1040): 0: 994: 38.67
+	Hs
		227767 LYN_HUMAN (129-215): 1.97e-09: 58.5: 22.47		MYO1B_HUMAN (3-1042): 0: 1059: 50.22
+	Hs
		840995 ABL2_HUMAN (4-139): 9.65e-22: 94.7: 34.04		MYO5A_HUMAN (1-1017): 0: 999: 29.28
+	Hs
		318243 LYN_HUMAN (129-215): 1.97e-09: 58.5: 22.47		MYO1D_HUMAN (7-1040): 0: 994: 38.67
+	Hs
		463489 LYN_HUMAN (129-215): 1.97e-09: 58.5: 22.47		MYO1E_HUMAN (9-722): 0: 587: 44.34
+	Hs
		776799 GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00		MYH11_HUMAN (709-1030): 7.8e-10: 65.3: 9.12
+	Hs
		772723 GRB2_HUMAN (1-217): 1.28e-70: 216: 100.00		MYH9_HUMAN (650-1043): 6.61e-09: 62.3: 11.41
+	Hs
		440414 FYN_HUMAN (161-215): 9.09e-13: 68.5: 31.58		MYH9_HUMAN (650-1043): 6.61e-09: 62.3: 11.41
+	Hs
		117127 J3QRU1_HUMAN (71-215): 6.6e-12: 65.8: 16.33		MYH9_HUMAN (650-1043): 6.61e-09: 62.3: 11.41
+	Hs
		463006 YES_HUMAN (71-215): 7.5e-12: 65.8: 16.33		MYH9_HUMAN (650-1043): 6.61e-09: 62.3: 11.41
+	Hs
		463377 LYN_HUMAN (129-215): 1.97e-09: 58.5: 22.47		MYH9_HUMAN (650-1043): 6.61e-09: 62.3: 11.41