HitPredict

Interactor 1: RAD51 (Q06609)
DNA repair protein RAD51 homolog 1 (HsRAD51) (hRAD51) (RAD51 homolog A)
Gene: RAD51

Interactor 2: WRN (Q14191)
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (DNA helicase, RecQ-like type 3) (RecQ protein-like 2) (Werner syndrome protein) [Includes: 3'-5' exonuclease (EC 3.1.-.-); ATP-dependent helicase (EC 5.6.2.4) (DNA 3'-5' helicase WRN)]
Gene: WRN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 0.60 0.634

The method score is based on:

Property Details
Experiments 17118963, 18562274
Identification Methods affinity chromatography technology, pull down, far western blotting, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000724 - double-strand break repair via homologous recombination
GO:0000781 - chromosome, telomeric region
GO:0003682 - chromatin binding
GO:0005524 - ATP binding
GO:0005634 - nucleus
and 8 others

more...
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 339
Hs

1 1432
+ Hs
+ Dm
+ Hs
+ Hs
+ Dm
+ Dm
+ Sc
+ Dm
+ Dm
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024