HitPredict

Interactor 1: RAC1 (P63000)
Ras-related C3 botulinum toxin substrate 1 (EC 3.6.5.2) (Cell migration-inducing gene 5 protein) (Ras-like protein TC25) (p21-Rac1)
Gene: RAC1

Interactor 2: LTOR1 (Q6IAA8)
Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18) (Protein associated with DRMs and endosomes) (p27Kip1-releasing factor from RhoA) (p27RF-Rho)
Gene: LAMTOR1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0070062 - extracellular exosome GO:0101003 - ficolin-1-rich granule membrane
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 192 Hs			1 161
+	Hs
		581114 RAC2_HUMAN (1-192): 2.74e-81: 241: 92.19		LTOR1_HUMAN (1-161): 1.94e-90: 262: 100.00
+	Hs
		1233482 RHOJ_HUMAN (2-189): 1.39e-80: 240: 60.64		LTOR1_HUMAN (1-161): 1.94e-90: 262: 100.00
+	Hs
		953509 RAC3_HUMAN (1-191): 3.71e-78: 233: 93.19		LTOR1_HUMAN (1-161): 1.94e-90: 262: 100.00
+	Hs
		955293 CDC42_HUMAN (1-192): 5.32e-78: 232: 70.31		LTOR1_HUMAN (1-161): 1.94e-90: 262: 100.00
+	Hs
		1015525 RHOG_HUMAN (1-192): 1.18e-77: 231: 71.35		LTOR1_HUMAN (1-161): 1.94e-90: 262: 100.00
+	Hs
		962162 RHOA_HUMAN (5-192): 1.33e-75: 226: 57.98		LTOR1_HUMAN (1-161): 1.94e-90: 262: 100.00
+	Hs
		466312 RHOC_HUMAN (5-192): 3.53e-73: 220: 57.45		LTOR1_HUMAN (1-161): 1.94e-90: 262: 100.00
+	Hs
		601334 RHOQ_HUMAN (4-190): 7.78e-73: 220: 63.16		LTOR1_HUMAN (1-161): 1.94e-90: 262: 100.00