HitPredict

Interactor 1: HSP7C (P63017)
Heat shock cognate 71 kDa protein (EC 3.6.4.10) (Heat shock 70 kDa protein 8)
Gene: Hspa8

Interactor 2: M3K14 (Q9WUL6)
Mitogen-activated protein kinase kinase kinase 14 (EC 2.7.11.25) (NF-kappa-beta-inducing kinase) (Serine/threonine-protein kinase NIK)
Gene: Map3k14

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25792747
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 646 Mm			1 942
+	Hs
		537765 HSP7C_HUMAN (1-646): 0: 972: 99.85		M3K14_HUMAN (1-942): 0: 741: 83.77
+	Hs
		761493 HS71L_HUMAN (2-646): 0: 969: 82.64		M3K14_HUMAN (1-942): 0: 741: 83.77
+	Hs
		600907 HSP76_HUMAN (6-646): 0: 958: 77.54		M3K14_HUMAN (1-942): 0: 741: 83.77
+	Hs
		516208 HS71B_HUMAN (1-646): 0: 951: 84.52		M3K14_HUMAN (1-942): 0: 741: 83.77
+	Hs
		536594 HSP7C_HUMAN (1-646): 0: 972: 99.85		AKT1_HUMAN (287-731): 7.88e-136: 417: 18.74
+	Hs
		600746 HSP76_HUMAN (6-646): 0: 958: 77.54		AKT1_HUMAN (287-731): 7.88e-136: 417: 18.74
+	Hs
		537084 HSP7C_HUMAN (1-646): 0: 972: 99.85		PAK1_HUMAN (162-676): 2.74e-129: 402: 20.91
+	Hs
		600801 HSP76_HUMAN (6-646): 0: 958: 77.54		PAK1_HUMAN (162-676): 2.74e-129: 402: 20.91
+	Hs
		537073 HSP7C_HUMAN (1-646): 0: 972: 99.85		STK4_HUMAN (396-652): 1.06e-98: 320: 29.89
+	Hs
		761379 HS71L_HUMAN (2-646): 0: 969: 82.64		STK4_HUMAN (396-652): 1.06e-98: 320: 29.89
+	Hs
		169916 HSP7C_HUMAN (1-646): 0: 972: 99.85		AURKA_HUMAN (291-654): 2.11e-98: 316: 21.73
+	Hs
		600800 HSP76_HUMAN (6-646): 0: 958: 77.54		STK4_HUMAN (396-652): 1.06e-98: 320: 29.89
+	Hs
		536666 HSP7C_HUMAN (1-646): 0: 972: 99.85		M3K8_HUMAN (346-685): 4.34e-29: 124: 27.37
+	Hs
		761340 HS71L_HUMAN (2-646): 0: 969: 82.64		M3K8_HUMAN (346-685): 4.34e-29: 124: 27.37
+	Hs
		537093 HSP7C_HUMAN (1-646): 0: 972: 99.85		M3K1_HUMAN (395-645): 2.33e-25: 115: 32.37
+	Hs
		761383 HS71L_HUMAN (2-646): 0: 969: 82.64		M3K1_HUMAN (395-645): 2.33e-25: 115: 32.37
+	Hs
		537780 HSP7C_HUMAN (1-646): 0: 972: 99.85		M3K3_HUMAN (408-614): 2.5e-22: 104: 34.70
+	Hs
		600803 HSP76_HUMAN (6-646): 0: 958: 77.54		M3K1_HUMAN (395-645): 2.33e-25: 115: 32.37
+	Hs
		761495 HS71L_HUMAN (2-646): 0: 969: 82.64		M3K3_HUMAN (408-614): 2.5e-22: 104: 34.70
+	Hs
		600912 HSP76_HUMAN (6-646): 0: 958: 77.54		M3K3_HUMAN (408-614): 2.5e-22: 104: 34.70