HitPredict

Interactor 1: 1433Z (P63104)
14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1) (KCIP-1)
Gene: YWHAZ

Interactor 2: TAB1 (Q15750)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 1) (TGF-beta-activated kinase 1-binding protein 1) (TAK1-binding protein 1)
Gene: TAB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	36931259
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction GO:0030324 - lung development
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 245 Hs			1 504
+	Hs
		971559 1433E_HUMAN (2-241): 9.95e-144: 403: 68.18		TAB1_HUMAN (1-504): 0: 525: 100.00
+	Hs
		691037 1433T_HUMAN (1-245): 2.61e-140: 395: 79.59		TAB1_HUMAN (1-504): 0: 525: 100.00
+	Hs
		729864 1433B_HUMAN (1-242): 9.05e-140: 393: 87.60		TAB1_HUMAN (1-504): 0: 525: 100.00
+	Hs
		966351 1433G_HUMAN (1-240): 2.38e-108: 314: 74.59		TAB1_HUMAN (1-504): 0: 525: 100.00
+	Hs
		1049321 1433F_HUMAN (2-240): 1.27e-107: 312: 74.49		TAB1_HUMAN (1-504): 0: 525: 100.00
+	Hs
		730610 1433S_HUMAN (1-237): 8.31e-104: 302: 71.97		TAB1_HUMAN (1-504): 0: 525: 100.00
+	Hs
		776946 1433Z_HUMAN (1-245): 1.67e-144: 405: 100.00		PPM1A_HUMAN (30-381): 4.26e-87: 274: 13.57
+	Hs
		290907 1433E_HUMAN (2-241): 9.95e-144: 403: 68.18		PPM1B_HUMAN (30-381): 3.59e-83: 267: 13.65
+	Hs
		690789 1433T_HUMAN (1-245): 2.61e-140: 395: 79.59		PPM1A_HUMAN (30-381): 4.26e-87: 274: 13.57
+	Hs
		186189 1433B_HUMAN (1-242): 9.05e-140: 393: 87.60		PPM1D_HUMAN (3-397): 1.42e-73: 245: 16.35
+	Ce
		112691 14332_CAEEL (3-241): 6.33e-139: 391: 81.59		TAB1_CAEEL (12-414): 1.51e-71: 234: 23.35