HitPredict

Interactor 1: CKAP4 (Q07065)
Cytoskeleton-associated protein 4 (63-kDa cytoskeleton-linking membrane protein) (Climp-63) (p63)
Gene: CKAP4

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 602 Hs			1 768
+	Hs
		1041911 MYH14_HUMAN (127-597): 5.01e-26: 116: 13.49		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		725157 MYH10_HUMAN (175-601): 2.98e-20: 98: 10.72		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		148780 CTRO_HUMAN (123-595): 4.03e-18: 91.2: 12.03		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042944 MRCKB_HUMAN (92-509): 4.22e-15: 81.1: 13.21		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		502829 LAMC1_HUMAN (304-590): 1.27e-11: 70: 12.71		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		724816 MYH9_HUMAN (299-602): 6.56e-11: 67.9: 16.78		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		675166 CLIP1_HUMAN (135-600): 1.12e-09: 63.8: 15.06		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042117 RBCC1_HUMAN (159-601): 1.73e-09: 63.3: 17.47		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		725158 MYH10_HUMAN (175-601): 2.98e-20: 98: 10.72		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1043039 FKB15_HUMAN (281-582): 9.2e-12: 70.4: 11.92		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		502830 LAMC1_HUMAN (304-590): 1.27e-11: 70: 12.71		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		725156 MYH10_HUMAN (175-601): 2.98e-20: 98: 10.72		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		502913 MYH3_HUMAN (34-597): 2.4e-18: 91.8: 11.38		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		724815 MYH9_HUMAN (299-602): 6.56e-11: 67.9: 16.78		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		969583 CENPE_HUMAN (130-597): 4.81e-10: 64.8: 18.51		CUL1_HUMAN (18-768): 0: 707: 30.57