Protein: UACA
Uveal autoantigen with coiled-coil domains and ankyrin repeats

Gene: UACA
Organism: Homo sapiens
Interactions: 153
UniProt ID: Q9BZF9

Gene Ontology (top 5):
GO:0003779 - actin binding
GO:0005576 - extracellular region
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

375915

RASK
GTPase KRas

3

20

High-throughput

0.827

High

725455

KAP1
cAMP-dependent protein kinase type I-beta regulatory subunit

2

4

High-throughput

0.783

High

1034974

GCYB1
Guanylate cyclase soluble subunit beta-1

2

0

High-throughput

0.770

High

374178

RASN
GTPase NRas

2

19

High-throughput

0.754

High

978276

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.754

High

171318

MYPT1
Protein phosphatase 1 regulatory subunit 12A

1

16

High-throughput

0.715

High

177304

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

1

18

High-throughput

0.698

High

1419864

PICK1
PRKCA-binding protein

4

1

High-throughput

0.692

High

1419855

P63
Tumor protein 63

1

7

Small-scale

0.691

High

1419876

CTDP1
RNA polymerase II subunit A C-terminal domain phosphatase

1

3

High-throughput

0.691

High

1238053

TIGD7
Tigger transposable element-derived protein 7

3

1

High-throughput

0.667

High

1419863

ANLN
Anillin

3

6

High-throughput

0.667

High

399622

VTNC
Vitronectin

3

1

High-throughput

0.662

High

890680

RGS3
Regulator of G-protein signaling 3

3

5

High-throughput

0.662

High

968432

PP1B
Serine/threonine-protein phosphatase PP1-beta catalytic subunit

2

8

High-throughput

0.635

High

1419868

MS18A
Protein Mis18-alpha

3

0

High-throughput

0.634

High

1392342

BORC6
BLOC-1-related complex subunit 6

4

2

High-throughput

0.633

High

1400221

PNMA5
Paraneoplastic antigen-like protein 5

2

1

High-throughput

0.628

High

1419858

SYNCI
Syncoilin

2

10

High-throughput

0.628

High

137512

BT3A1
Butyrophilin subfamily 3 member A1

1

10

High-throughput

0.618

High

127792

IKBE
NF-kappa-B inhibitor epsilon

1

20

High-throughput

0.618

High

132282

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

11

Small-scale

0.618

High

331296

KI20A
Kinesin-like protein KIF20A

1

17

High-throughput

0.618

High

374905

RASH
GTPase HRas

1

14

High-throughput

0.618

High

401443

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

15

High-throughput

0.618

High

463746

LYN
Tyrosine-protein kinase Lyn

1

11

High-throughput

0.618

High

541673

FGFR1
Fibroblast growth factor receptor 1

1

20

High-throughput

0.618

High

648656

FGFR4
Fibroblast growth factor receptor 4

1

20

High-throughput

0.618

High

710469

EPHA2
Ephrin type-A receptor 2

1

20

High-throughput

0.618

High

710889

EPHB2
Ephrin type-B receptor 2

1

15

High-throughput

0.618

High

765014

CTNB1
Catenin beta-1

1

9

High-throughput

0.618

High

845787

MUC18
Cell surface glycoprotein MUC18

1

8

High-throughput

0.618

High

953653

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

1015751

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.618

High

1048992

REL
Proto-oncogene c-Rel

1

9

High-throughput

0.618

High

1140808

KIF14
Kinesin-like protein KIF14

1

9

High-throughput

0.618

High

1145095

RAB35
Ras-related protein Rab-35

1

8

High-throughput

0.618

High

1153019

MYLK
Myosin light chain kinase, smooth muscle

1

13

High-throughput

0.618

High

1255417

TRI67
Tripartite motif-containing protein 67

1

20

High-throughput

0.618

High

1380145

FBXW7
F-box/WD repeat-containing protein 7

1

18

High-throughput

0.618

High

1407237

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

7

High-throughput

0.618

High

1419852

UACA
Uveal autoantigen with coiled-coil domains and ankyrin repeats

1

18

High-throughput

0.618

High

1419860

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

1419870

HDAC6
Protein deacetylase HDAC6

1

15

High-throughput

0.618

High

1146150

K1H1
Keratin, type I cuticular Ha1

2

20

High-throughput

0.606

High

1419871

UBQL2
Ubiquilin-2

2

6

High-throughput

0.606

High

1395073

JPH4
Junctophilin-4

3

5

High-throughput

0.604

High

691399

1433T
14-3-3 protein theta

2

20

High-throughput

0.601

High

730215

1433B
14-3-3 protein beta/alpha

2

20

High-throughput

0.601

High

966842

1433G
14-3-3 protein gamma

2

20

High-throughput

0.601

High

990697

1433Z
14-3-3 protein zeta/delta

2

20

High-throughput

0.601

High

1049749

1433F
14-3-3 protein eta

2

20

High-throughput

0.601

High

1419872

TNIK
TRAF2 and NCK-interacting protein kinase

1

20

High-throughput

0.590

High

1419877

CD2AP
CD2-associated protein

1

7

High-throughput

0.590

High

230102

SAHH2
S-adenosylhomocysteine hydrolase-like protein 1

2

0

High-throughput

0.580

High

942861

BCAR1
Breast cancer anti-estrogen resistance protein 1

1

17

High-throughput

0.575

High

987920

GRB2
Growth factor receptor-bound protein 2

1

18

High-throughput

0.575

High

1405519

ZBT18
Zinc finger and BTB domain-containing protein 18

1

7

High-throughput

0.575

High

1246430

CORO6
Coronin-6

2

11

High-throughput

0.574

High

1230243

K1C40
Keratin, type I cytoskeletal 40

1

20

High-throughput

0.573

High

396882

ESR1
Estrogen receptor

2

20

High-throughput

0.571

High

1208736

RTP2
Receptor-transporting protein 2

2

1

High-throughput

0.553

High

1295771

CC125
Coiled-coil domain-containing protein 125

2

1

High-throughput

0.553

High

1151857

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.553

High

1419866

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

17

Small-scale

0.552

High

1419861

JPH1
Junctophilin-1

1

5

High-throughput

0.541

High

250809

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

6

High-throughput

0.536

High

277954

SH3L1
Adapter SH3BGRL

1

3

High-throughput

0.536

High

344995

WIZ
Protein Wiz

1

1

High-throughput

0.536

High

472402

FGF4
Fibroblast growth factor 4

1

12

High-throughput

0.536

High

659583

CRCM
Colorectal mutant cancer protein

1

16

High-throughput

0.536

High

773002

MYH9
Myosin-9

1

15

High-throughput

0.536

High

856904

BAG6
Large proline-rich protein BAG6

1

7

High-throughput

0.536

High

1009624

CXCL6
C-X-C motif chemokine 6

1

1

High-throughput

0.536

High

1161385

HIF1A
Hypoxia-inducible factor 1-alpha

1

6

High-throughput

0.536

High

1357205

BRK1
Protein BRICK1

1

1

High-throughput

0.536

High

1405043

SORT
Sortilin

1

3

High-throughput

0.536

High

1419854

TARA
TRIO and F-actin-binding protein

1

16

High-throughput

0.536

High

1419857

RABE2
Rab GTPase-binding effector protein 2

1

15

High-throughput

0.536

High

1419875

MB212
Protein mab-21-like 2

1

3

High-throughput

0.536

High

437331

K2C8
Keratin, type II cytoskeletal 8

1

11

High-throughput

0.515

High

474961

VIME
Vimentin

1

13

High-throughput

0.515

High

1224771

RN213
E3 ubiquitin-protein ligase RNF213

1

0

High-throughput

0.513

High

340672

STABP
STAM-binding protein

1

1

High-throughput

0.508

High

354033

CX001
Putative transmembrane protein CXorf1

1

1

High-throughput

0.489

High

1093771

GAGE5
G antigen 5

1

1

High-throughput

0.489

High

1179850

INSY1
Inhibitory synaptic factor 1

1

1

High-throughput

0.489

High

1214191

LITD1
LINE-1 type transposase domain-containing protein 1

1

1

High-throughput

0.489

High

1228714

C102B
Coiled-coil domain-containing protein 102B

1

18

High-throughput

0.489

High

1315635

ENTD1
ENTH domain-containing protein 1

1

4

High-throughput

0.489

High

1398890

RILP
Rab-interacting lysosomal protein

1

5

High-throughput

0.489

High

1419859

IFT22
Intraflagellar transport protein 22 homolog

1

2

High-throughput

0.489

High

239615

MED14
Mediator of RNA polymerase II transcription subunit 14

1

5

High-throughput

0.481

High

164080

NDC80
Kinetochore protein NDC80 homolog

1

17

High-throughput

0.479

High

242838

PRKN
E3 ubiquitin-protein ligase parkin

1

5

High-throughput

0.479

High

248078

NUPR1
Nuclear protein 1

1

2

High-throughput

0.479

High

340231

PCNT
Pericentrin

1

20

High-throughput

0.479

High

346289

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

14

High-throughput

0.479

High

373083

MYC
Myc proto-oncogene protein

1

12

High-throughput

0.479

High

425622

ISG15
Ubiquitin-like protein ISG15

1

8

High-throughput

0.479

High

461900

HS90A
Heat shock protein HSP 90-alpha

1

14

High-throughput

0.479

High

556325

CADH1
Cadherin-1

1

6

High-throughput

0.479

High

604187

CXA1
Gap junction alpha-1 protein

1

7

High-throughput

0.479

High

623520

RO52
E3 ubiquitin-protein ligase TRIM21

1

9

High-throughput

0.479

High

630030

BTF3
Transcription factor BTF3

1

5

High-throughput

0.479

High

657678

GCSP
Glycine dehydrogenase

1

1

High-throughput

0.479

High

775302

FUS
RNA-binding protein FUS

1

4

High-throughput

0.479

High

775905

HNF1B
Hepatocyte nuclear factor 1-beta

1

1

High-throughput

0.479

High

786828

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

8

High-throughput

0.479

High

862427

YAP1
Transcriptional coactivator YAP1

1

20

Small-scale

0.479

High

869081

TISD
mRNA decay activator protein ZFP36L2

1

3

High-throughput

0.479

High

923634

TTC3
E3 ubiquitin-protein ligase TTC3

1

16

High-throughput

0.479

High

936442

AFAD
Afadin

1

20

High-throughput

0.479

High

957506

UBC12
NEDD8-conjugating enzyme Ubc12

1

7

High-throughput

0.479

High

974960

TYB4
Thymosin beta-4

1

3

High-throughput

0.479

High

1024821

VIGLN
Vigilin

1

13

High-throughput

0.479

High

1038996

NUCB1
Nucleobindin-1

1

1

High-throughput

0.479

High

1087268

STX4
Syntaxin-4

1

9

High-throughput

0.479

High

1138024

TNIP1
TNFAIP3-interacting protein 1

1

18

High-throughput

0.479

High

1161652

IF16
Gamma-interferon-inducible protein 16

1

2

High-throughput

0.479

High

1197561

PAN2
PAN2-PAN3 deadenylation complex catalytic subunit PAN2

1

9

High-throughput

0.479

High

1253236

FGD5
FYVE, RhoGEF and PH domain-containing protein 5

1

20

High-throughput

0.479

High

1271849

MEPCE
7SK snRNA methylphosphate capping enzyme

1

4

High-throughput

0.479

High

1289103

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

12

Small-scale

0.479

High

1349760

FBX25
F-box only protein 25

1

6

High-throughput

0.479

High

1353264

PARD3
Partitioning defective 3 homolog

1

12

High-throughput

0.479

High

1381953

CK052
Uncharacterized protein C11orf52

1

4

High-throughput

0.479

High

1404744

RING2
E3 ubiquitin-protein ligase RING2

1

20

High-throughput

0.479

High

1410362

MEP50
Methylosome protein WDR77

1

10

High-throughput

0.479

High

1419853

RNF38
E3 ubiquitin-protein ligase RNF38

1

7

Small-scale

0.479

High

1419856

DNJC5
DnaJ homolog subfamily C member 5

1

10

High-throughput

0.479

High

1419862

CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD

1

4

High-throughput

0.479

High

1419873

ALK
ALK tyrosine kinase receptor

1

20

High-throughput

0.479

High

1419874

TRI33
E3 ubiquitin-protein ligase TRIM33

1

13

High-throughput

0.479

High

229568

NRDC
Nardilysin

1

0

Small-scale

0.458

High

1289847

VASH2
Tubulinyl-Tyr carboxypeptidase 2

1

0

High-throughput

0.458

High

1383401

ZUP1
Zinc finger-containing ubiquitin peptidase 1

1

0

High-throughput

0.458

High

1419867

TRM1
tRNA

1

0

High-throughput

0.458

High

1419865

DISC1
Disrupted in schizophrenia 1 protein

1

7

High-throughput

0.457

High

564337

CFTR
Cystic fibrosis transmembrane conductance regulator

1

12

High-throughput

0.445

High

765861

BMI1
Polycomb complex protein BMI-1

1

11

High-throughput

0.445

High

1234943

PKHA7
Pleckstrin homology domain-containing family A member 7

1

20

High-throughput

0.445

High

1258567

CR3L2
Cyclic AMP-responsive element-binding protein 3-like protein 2

1

4

High-throughput

0.445

High

1404367

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.438

High

1159826

OCLN
Occludin

1

3

High-throughput

0.437

High

1250195

LRC31
Leucine-rich repeat-containing protein 31

1

5

High-throughput

0.437

High

1419869

CELR3
Cadherin EGF LAG seven-pass G-type receptor 3

1

4

Small-scale

0.417

High

1167112

WHAL1
Putative WASP homolog-associated protein with actin, membranes and microtubules-like protein 1

1

2

High-throughput

0.407

High

1340415

RASF8
Ras association domain-containing protein 8

1

2

High-throughput

0.407

High

1392987

CC120
Coiled-coil domain-containing protein 120

1

1

High-throughput

0.407

High

1419878

CCD61
Centrosomal protein CCDC61

1

1

Small-scale

0.407

High

261971

RNH1
Ribonuclease H1

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025