Interactor 1: MCL1 (Q07820)
Induced myeloid leukemia cell differentiation protein Mcl-1 (Bcl-2-like protein 3) (Bcl2-L-3) (Bcl-2-related protein EAT/mcl1) (mcl1/EAT)
Gene: MCL1
Interactor 2: APR (Q13794)
Phorbol-12-myristate-13-acetate-induced protein 1 (PMA-induced protein 1) (Immediate-early-response protein APR) (Protein Noxa)
Gene: PMAIP1
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.988 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 27517746, 15694340, 15901672, 32913203, 27166195, 22361683, 15721256, 16697956, 26045051, 29799788, 32094511, 33961781, 27701804, 36346691, 21613222, 21139584, 19148187, 23341456, 22219388, 21454712 and 2 others
more... |
| Identification Methods | affinity chromatography technology, unspecified method, pull down, surface plasmon resonance, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Bcl-2~PMAIP1 |
| Common GO terms | GO:0001836 - release of cytochrome c from mitochondria GO:0005634 - nucleus GO:0005739 - mitochondrion GO:0005741 - mitochondrial outer membrane GO:0005829 - cytosol and 3 others more... |
| Homologous interactions | 7 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
