Protein: CUL1
Cullin homolog 1 (Lin-19 homolog protein)

Gene: CUL1
Organism: Drosophila melanogaster
Interactions: 39
UniProt ID: Q24311

Gene Ontology (top 5):
GO:0002785 - negative regulation of antimicrobial peptide production
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0016567 - protein ubiquitination
GO:0019005 - SCF ubiquitin ligase complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1173425

Q9VDE3
LD08669p

4

20

Small-scale

0.886

High

305466

O77430
GEO01111p1

4

20

Small-scale

0.861

High

1173437

RBX1A
RING-box protein 1A

4

20

Small-scale

0.861

High

1173427

NEDD8
Ubiquitin-like protein NEDD8

3

20

Small-scale

0.827

High

1173428

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

20

Small-scale

0.724

High

1173422

FBSP1
F-box/SPRY domain-containing protein 1

1

20

Small-scale

0.665

High

1173432

UBC2M
Nedd8-conjugating enzyme UbcE2M

1

20

Small-scale

0.647

High

1173412

CUL1
Cullin homolog 1

1

17

Small-scale

0.618

High

1173416

Q7KJ69
GEO01805p1

1

20

High-throughput

0.618

High

1173421

RBX1B
RING-box protein 1B

1

20

Small-scale

0.618

High

1173426

Q9VF10
F-box and leucine-rich repeat protein 7

1

20

Small-scale

0.618

High

1173420

NUTC
Protein nutcracker

1

0

Small-scale

0.586

High

624307

CI
Transcriptional activator cubitus interruptus

2

20

Small-scale

0.584

High

1173415

Q7JQL2
LD20463p

1

20

Small-scale

0.553

High

1173435

Q9W200
EF-hand domain-containing protein

1

1

High-throughput

0.508

High

1173423

UBA3
Nedd8-activating enzyme E1 catalytic subunit

1

4

Small-scale

0.501

High

1173413

MERH
Moesin/ezrin/radixin homolog 2

1

5

High-throughput

0.494

High

683045

UBCD1
Ubiquitin-conjugating enzyme E2-17 kDa

1

16

High-throughput

0.492

High

57334

DLISH
SH3 domain-containing protein Dlish

1

2

Small-scale

0.479

High

356644

PLK4
Serine/threonine-protein kinase PLK4

1

8

Small-scale

0.479

High

931748

CCNE
G1/S-specific cyclin-E

1

6

Small-scale

0.479

High

1059287

EXPA
Protein expanded

1

8

Small-scale

0.479

High

1173417

TERA
Transitional endoplasmic reticulum ATPase TER94

1

12

Small-scale

0.479

High

1173430

Q9VNX7
GH10766p

1

2

High-throughput

0.479

High

1173433

SMN
Survival motor neuron protein

1

2

Small-scale

0.479

High

1173436

Q9W215
GEO03726p1

1

1

Small-scale

0.479

High

1173431

CH60B
60 kDa heat shock protein homolog 1, mitochondrial

1

9

High-throughput

0.464

High

1173429

Q9VM76
GH14043p

1

0

Small-scale

0.458

High

1173434

Q9W1N8
LD45221p

1

0

Small-scale

0.458

High

198228

O18683
LD42724p

1

10

High-throughput

0.445

High

119579

M9PAY7
Pi3K21B, isoform C

1

10

High-throughput

0.437

High

1173419

ENC
Protein encore

1

3

Small-scale

0.437

High

1173424

CAD99
Cadherin-99C

1

8

Small-scale

0.437

High

118847

M9NFI9
Neurabin-1

1

10

High-throughput

0.407

High

1014688

CYC2
Cytochrome c-2

1

1

High-throughput

0.407

High

1173414

Q6QU65
ADAM metalloprotease

1

6

High-throughput

0.407

High

1173418

Q8IRE7
PAN2-PAN3 deadenylation complex subunit PAN3

1

5

High-throughput

0.407

High

450811

CH38
Chorion protein S38

1

0

High-throughput

0.265

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025