Interactor 1: MCL1 (Q07820)
Induced myeloid leukemia cell differentiation protein Mcl-1 (Bcl-2-like protein 3) (Bcl2-L-3) (Bcl-2-related protein EAT/mcl1) (mcl1/EAT)
Gene: MCL1

Interactor 2: BECN1 (Q14457)
Beclin-1 (Coiled-coil myosin-like BCL2-interacting protein) (Protein GT197) [Cleaved into: Beclin-1-C 35 kDa; Beclin-1-C 37 kDa]
Gene: BECN1

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.60 1.00 0.776

The method score is based on:

Property Details
Experiments 22219388, 21139567
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains BH3~Bcl-2
Common GO terms GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0043066 - negative regulation of apoptotic process
Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 350
Hs

1 450
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+ Mm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024