Protein: CUL1
Cullin-1 (CUL-1)

Gene: CUL1
Organism: Mus musculus
Interactions: 35
UniProt ID: Q9WTX6

Gene Ontology (top 5):
GO:0005886 - plasma membrane
GO:0006511 - ubiquitin-dependent protein catabolic process
GO:0006513 - protein monoubiquitination
GO:0006915 - apoptotic process
GO:0008283 - cell population proliferation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1490137

SKP1
S-phase kinase-associated protein 1

6

20

Small-scale

0.936

High

1490142

SKP2
S-phase kinase-associated protein 2

4

20

Small-scale

0.873

High

1190511

FBW1A
F-box/WD repeat-containing protein 1A

3

20

Small-scale

0.830

High

1353853

FBXW7
F-box/WD repeat-containing protein 7

3

20

Small-scale

0.827

High

984057

RBX1
E3 ubiquitin-protein ligase RBX1

2

20

Small-scale

0.776

High

1296681

FBXW8
F-box/WD repeat-containing protein 8

2

20

Small-scale

0.776

High

1295889

FXL21
F-box/LRR-repeat protein 21

2

3

Small-scale

0.744

High

1298073

FBXL3
F-box/LRR-repeat protein 3

2

3

Small-scale

0.744

High

1455795

Q9QUH1
F-box/WD repeat-containing protein 2

2

20

Small-scale

0.675

High

1354019

CUL7
Cullin-7

1

5

Small-scale

0.665

High

1423932

FXL20
F-box/LRR-repeat protein 20

1

20

Small-scale

0.618

High

1253432

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

20

Small-scale

0.618

High

1257462

SPOP
Speckle-type POZ protein

1

20

High-throughput

0.618

High

1282066

FBX2
F-box only protein 2

1

8

Small-scale

0.618

High

1490140

CUL1
Cullin-1

1

16

Small-scale

0.618

High

1253452

CAND2
Cullin-associated NEDD8-dissociated protein 2

1

20

Small-scale

0.595

High

1423581

FBX32
F-box only protein 32

2

4

Small-scale

0.584

High

1189416

Q3TJW2
F-box only protein 15

1

1

Small-scale

0.553

High

1243924

FBX42
F-box only protein 42

1

20

Small-scale

0.553

High

1440942

FBXW4
F-box/WD repeat-containing protein 4

1

20

Small-scale

0.553

High

558946

MYOG
Myogenin

1

5

Small-scale

0.512

High

204527

PKD2
Polycystin-2

1

5

Small-scale

0.479

High

772586

IRS1
Insulin receptor substrate 1

1

15

Small-scale

0.479

High

1362814

EED
Polycomb protein EED

1

20

High-throughput

0.479

High

1424315

WWTR1
WW domain-containing transcription regulator protein 1

1

6

Small-scale

0.479

High

1490141

CARM1
Histone-arginine methyltransferase CARM1

1

10

Small-scale

0.479

High

1440909

SPAG6
Sperm-associated antigen 6

1

16

High-throughput

0.439

High

204592

CHK1
Serine/threonine-protein kinase Chk1

1

2

Small-scale

0.437

High

703991

DUS1
Dual specificity protein phosphatase 1

1

3

Small-scale

0.437

High

958752

CSN2
COP9 signalosome complex subunit 2

1

20

Small-scale

0.437

High

986319

FBX40
F-box only protein 40

1

3

Small-scale

0.437

High

1021083

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog

1

2

Small-scale

0.437

High

1297506

THIM
3-ketoacyl-CoA thiolase, mitochondrial

1

5

Small-scale

0.437

High

50996

MPEG1
Macrophage-expressed gene 1 protein

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025