HitPredict

Interactor 1: LRP1 (Q07954)
Prolow-density lipoprotein receptor-related protein 1 (LRP-1) (Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E receptor) (APOER) (CD antigen CD91) [Cleaved into: Low-density lipoprotein receptor-related protein 1 85 kDa subunit (LRP-85); Low-density lipoprotein receptor-related protein 1 515 kDa subunit (LRP-515); Low-density lipoprotein receptor-related protein 1 intracellular domain (LRPICD)]
Gene: LRP1

Interactor 2: SCMC3 (Q9BV35)
Mitochondrial adenyl nucleotide antiporter SLC25A23 (Mitochondrial ATP-Mg/Pi carrier protein 2) (Short calcium-binding mitochondrial carrier protein 3) (SCaMC-3) (Solute carrier family 25 member 23)
Gene: SLC25A23

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005509 - calcium ion binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 4544 Hs			1 468
+	Hs
		992673 LRP1_HUMAN (24-4544): 0: 3520: 100.00		SCMC2_HUMAN (8-360): 2.46e-51: 182: 19.59
+	Hs
		518326 LRP1_HUMAN (24-4544): 0: 3520: 100.00		ADT3_HUMAN (114-363): 2.97e-38: 142: 22.01
+	Hs
		397353 LRP1_HUMAN (24-4544): 0: 3520: 100.00		ADT2_HUMAN (114-362): 2.26e-36: 137: 21.32
+	Hs
		992672 LRP1_HUMAN (24-4544): 0: 3520: 100.00		KMCP1_HUMAN (166-269): 1.07e-15: 79.3: 16.51