HitPredict

Interactor 1: SRSF1 (Q07955)
Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit)
Gene: SRSF1

Interactor 2: NCBP1 (Q09161)
Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit)
Gene: NCBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	32960270
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	MIF4G_like~RRM_1, MIF4G_like_2~RRM_1
Common GO terms	GO:0000380 - alternative mRNA splicing, via spliceosome GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005634 - nucleus and 2 others more... GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 790
+	Hs
		998032 SRSF9_HUMAN (1-239): 2.72e-66: 206: 60.25		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Hs
		998033 SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Hs
		998034 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Hs
		516479 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Hs
		998068 SRSF7_HUMAN (14-105): 7.34e-23: 94.8: 40.22		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Hs
		998037 PABP4_HUMAN (118-200): 2.19e-13: 71.2: 16.67		NCBP1_HUMAN (1-790): 0: 1180: 100.00
+	Sc
		376713 PABP_YEAST (123-203): 2.42e-12: 68.1: 22.73		NCBP1_YEAST (3-693): 2.4e-99: 329: 17.53