HitPredict

Interactor 1: SRSF1 (Q07955)
Serine/arginine-rich splicing factor 1 (Alternative-splicing factor 1) (ASF-1) (Splicing factor, arginine/serine-rich 1) (pre-mRNA-splicing factor SF2, P33 subunit)
Gene: SRSF1

Interactor 2: U5S1 (Q15029)
116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)
Gene: EFTUD2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28515276
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016607 - nuclear speck and 1 others more... GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 248 Hs			1 972
+	Hs
		1028659 SRSF5_HUMAN (14-183): 8.03e-61: 194: 41.48		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		1028919 SRSF6_HUMAN (17-200): 2.58e-57: 187: 40.51		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		516526 PABP1_HUMAN (8-203): 7.41e-38: 141: 16.67		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		951968 SRSF3_HUMAN (15-99): 9.33e-28: 105: 43.53		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		1064346 SRSF7_HUMAN (14-105): 7.34e-23: 94.8: 40.22		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Hs
		1031337 PABP4_HUMAN (118-200): 2.19e-13: 71.2: 16.67		U5S1_HUMAN (1-972): 0: 1062: 100.00
+	Sp
		292934 PABP_SCHPO (123-203): 6.82e-12: 66.6: 20.46		SN114_SCHPO (1-970): 0: 928: 54.22