HitPredict

Interactor 1: GRAP (Q08012)
Growth factor receptor-bound protein 2 (Downstream of receptor kinase) (Protein enhancer of sevenless 2B)
Gene: drk

Interactor 2: Y34F (Q9W5D0)
Uncharacterized protein CG43867
Gene: CG43867

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.555

Property	Details
Experiments	14605208
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	PH~SH3_1
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 211 Dm			1 1820
+	Hs
		663972 GRB2_HUMAN (1-210): 1.39e-64: 200: 62.62		PTN4_HUMAN (1384-1819): 3.88e-87: 309: 11.93
+	Hs
		924798 GRB2_HUMAN (1-210): 1.39e-64: 200: 62.62		ARAP1_HUMAN (820-1604): 1.24e-82: 302: 14.22
+	Hs
		337358 ABL1_HUMAN (4-138): 2.7e-23: 99: 36.43		PTN4_HUMAN (1384-1819): 3.88e-87: 309: 11.93
+	Hs
		1285194 SH3K1_HUMAN (3-60): 1.52e-13: 70.4: 27.12		PKHA5_HUMAN (785-1773): 2.42e-95: 337: 13.47
+	Hs
		557617 NCK1_HUMAN (5-143): 2.4e-20: 89.4: 32.35		PTN4_HUMAN (1384-1819): 3.88e-87: 309: 11.93
+	Hs
		663965 CRK_HUMAN (48-209): 9e-20: 87: 29.69		PTN4_HUMAN (1384-1819): 3.88e-87: 309: 11.93
+	Hs
		557775 NCK1_HUMAN (5-143): 2.4e-20: 89.4: 32.35		ARAP1_HUMAN (820-1604): 1.24e-82: 302: 14.22
+	Hs
		802704 CRK_HUMAN (48-209): 9e-20: 87: 29.69		ARAP1_HUMAN (820-1604): 1.24e-82: 302: 14.22
+	Hs
		337606 ABL1_HUMAN (4-138): 2.7e-23: 99: 36.43		TLN2_HUMAN (1311-1814): 2.02e-75: 282: 15.87
+	Hs
		412035 FYN_HUMAN (160-211): 2.56e-12: 66.9: 27.78		PTN4_HUMAN (1384-1819): 3.88e-87: 309: 11.93
+	Hs
		1197822 SH3K1_HUMAN (3-60): 1.52e-13: 70.4: 27.12		PHLB2_HUMAN (303-1003): 1.04e-83: 304: 15.96
+	Hs
		1285175 SH3K1_HUMAN (3-60): 1.52e-13: 70.4: 27.12		ARAP1_HUMAN (820-1604): 1.24e-82: 302: 14.22
+	Hs
		337601 ABL1_HUMAN (4-138): 2.7e-23: 99: 36.43		E41L3_HUMAN (1381-1803): 3.72e-72: 266: 14.59
+	Hs
		924812 GRB2_HUMAN (1-210): 1.39e-64: 200: 62.62		CYH2_HUMAN (824-1021): 2.65e-43: 165: 18.83
+	Hs
		802784 CRK_HUMAN (48-209): 9e-20: 87: 29.69		E41L3_HUMAN (1381-1803): 3.72e-72: 266: 14.59
+	Hs
		412284 FYN_HUMAN (160-211): 2.56e-12: 66.9: 27.78		ARAP2_HUMAN (492-1515): 2.66e-74: 277: 13.55
+	Hs
		1262750 SH3K1_HUMAN (3-60): 1.52e-13: 70.4: 27.12		ARAP3_HUMAN (750-1074): 1.11e-53: 209: 19.37
+	Hs
		924876 GRB2_HUMAN (1-210): 1.39e-64: 200: 62.62		PKHA2_HUMAN (858-1009): 5.89e-13: 75.3: 21.88
+	Hs
		299283 Q96D37_HUMAN (2-60): 5.72e-14: 72: 37.29		FARP2_HUMAN (835-1020): 2.3e-15: 84.2: 14.95
+	Hs
		299235 VAV_HUMAN (2-60): 7.85e-14: 71.6: 37.29		FARP2_HUMAN (835-1020): 2.3e-15: 84.2: 14.95