HitPredict

Interactor 1: ACTBL (Q562R1)
Beta-actin-like protein 2 (Kappa-actin)
Gene: ACTBL2

Interactor 2: SRCAP (Q6ZRS2)
Helicase SRCAP (EC 3.6.4.-) (Domino homolog 2) (Snf2-related CBP activator)
Gene: SRCAP

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	1.00	0.811

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~HSA, Actin~SNF2-rel_dom
Common GO terms	GO:0005524 - ATP binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 376 Hs			1 3230
+	Hs
		952913 ACTB_HUMAN (3-376): 0: 595: 91.71		SRCAP_HUMAN (1-3230): 0: 1073: 100.00
+	Hs
		993223 ACTG_HUMAN (3-376): 0: 594: 91.44		SRCAP_HUMAN (1-3230): 0: 1073: 100.00
+	Hs
		995656 ACTC_HUMAN (2-376): 0: 589: 88.27		SRCAP_HUMAN (1-3230): 0: 1073: 100.00
+	Hs
		952823 ACTB_HUMAN (3-376): 0: 595: 91.71		CHD4_HUMAN (2010-2629): 6.48e-85: 314: 20.16
+	Hs
		995594 ACTC_HUMAN (2-376): 0: 589: 88.27		CHD4_HUMAN (2010-2629): 6.48e-85: 314: 20.16
+	Hs
		243593 ACTC_HUMAN (2-376): 0: 589: 88.27		SMCA5_HUMAN (2001-2412): 9.24e-78: 284: 26.02
+	Dm
		534416 ACT1_DROME (1-376): 0: 597: 90.69		BRM_DROME (2005-2428): 2.36e-70: 266: 22.48
+	Dm
		386972 ACT2_DROME (1-376): 0: 595: 90.16		BRM_DROME (2005-2428): 2.36e-70: 266: 22.48
+	Hs
		953175 ACTB_HUMAN (3-376): 0: 595: 91.71		INO80_HUMAN (2003-2492): 6.68e-70: 264: 25.81
+	Hs
		903177 ACTBL_HUMAN (1-376): 0: 615: 100.00		SMCA2_HUMAN (2009-2447): 1.85e-56: 220: 23.32
+	Xl
		313500 ACTB_XENLA (3-376): 0: 594: 91.18		Q4VQ79_XENLA (2011-2447): 2.85e-61: 236: 22.55
+	Hs
		903297 ACTB_HUMAN (3-376): 0: 595: 91.71		SMCA4_HUMAN (2009-2447): 9.73e-57: 221: 21.12
+	Hs
		903306 ACTG_HUMAN (3-376): 0: 594: 91.44		SMCA4_HUMAN (2009-2447): 9.73e-57: 221: 21.12
+	Hs
		903307 ACTC_HUMAN (2-376): 0: 589: 88.27		SMCA4_HUMAN (2009-2447): 9.73e-57: 221: 21.12
+	Hs
		903124 ACTC_HUMAN (2-376): 0: 589: 88.27		SMCA2_HUMAN (2009-2447): 1.85e-56: 220: 23.32
+	Hs
		953042 ACTB_HUMAN (3-376): 0: 595: 91.71		EP400_HUMAN (1085-1716): 1.9e-11: 73: 13.39
+	Hs
		993296 ACTG_HUMAN (3-376): 0: 594: 91.44		EP400_HUMAN (1085-1716): 1.9e-11: 73: 13.39
+	Mm
		993108 ACTG_MOUSE (3-376): 0: 594: 91.44		EP400_MOUSE (1024-1716): 9.49e-10: 67.2: 13.77
+	Mm
		993092 ACTG_MOUSE (3-376): 0: 594: 91.44		SMCA4_MOUSE (1328-1647): 5e-09: 64.6: 16.46
+	Mm
		993102 ACTG_MOUSE (3-376): 0: 594: 91.44		SMCA2_MOUSE (1333-1678): 8.31e-09: 63.8: 14.16