HitPredict

Interactor 1: TLE5 (Q08117)
TLE family member 5 (Amino-terminal enhancer of split) (Amino enhancer of split) (Gp130-associated protein GAM) (Grg-5) (Groucho-related protein 5) (Protein ESP1) (Protein GRG) (TLE family member 5, transcriptional modulator)
Gene: TLE5

Interactor 2: NFIX (Q14938)
Nuclear factor 1 X-type (NF1-X) (Nuclear factor 1/X) (CCAAT-box-binding transcription factor) (CTF) (Nuclear factor I/X) (NF-I/X) (NFI-X) (TGGCA-binding protein)
Gene: NFIX

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35140242
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 197 Hs			1 502
+	Hs
		980606 TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50		NFIX_HUMAN (1-502): 6.2e-159: 462: 100.00
+	Hs
		980754 TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50		NFIX_HUMAN (1-502): 6.2e-159: 462: 100.00
+	Hs
		980594 TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50		NFIA_HUMAN (1-502): 1.62e-118: 359: 66.47
+	Hs
		443170 TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50		NFIC_HUMAN (3-502): 5.37e-114: 348: 53.43
+	Hs
		980739 TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50		NFIA_HUMAN (1-502): 1.62e-118: 359: 66.47
+	Hs
		443171 TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50		NFIC_HUMAN (3-502): 5.37e-114: 348: 53.43
+	Hs
		993404 TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00		NFIA_HUMAN (1-502): 1.62e-118: 359: 66.47
+	Hs
		135106 TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50		NFIB_HUMAN (1-419): 4.58e-101: 311: 58.69
+	Hs
		135107 TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50		NFIB_HUMAN (1-419): 4.58e-101: 311: 58.69
+	Hs
		135111 TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00		NFIB_HUMAN (1-419): 4.58e-101: 311: 58.69
+	Hs
		123919 TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00		SPT5H_HUMAN (144-357): 1.74e-12: 71.9: 13.60