HitPredict

Interactor 1: ACTH (P63267)
Actin, gamma-enteric smooth muscle (EC 3.6.4.-) (Alpha-actin-3) (Gamma-2-actin) (Smooth muscle gamma-actin) [Cleaved into: Actin, gamma-enteric smooth muscle, intermediate form]
Gene: ACTG2

Interactor 2: TRIM6 (Q9C030)
Tripartite motif-containing protein 6 (EC 2.3.2.27) (RING finger protein 89) (RING-type E3 ubiquitin transferase TRIM6)
Gene: TRIM6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	31992359, 38515377
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 376 Hs			1 488
+	Hs
		623371 ACTBL_HUMAN (1-376): 0: 713: 87.77		RO52_HUMAN (1-485): 1.6e-152: 444: 44.51
+	Hs
		953083 ACTB_HUMAN (1-376): 0: 601: 93.35		TRIM6_HUMAN (1-488): 2.05e-158: 460: 100.00
+	Hs
		996531 ACTS_HUMAN (2-376): 0: 598: 98.13		TRIM6_HUMAN (1-488): 2.05e-158: 460: 100.00
+	Hs
		623217 ACTB_HUMAN (1-376): 0: 601: 93.35		RO52_HUMAN (1-485): 1.6e-152: 444: 44.51
+	Hs
		623263 ACTG_HUMAN (3-376): 0: 601: 94.39		RO52_HUMAN (1-485): 1.6e-152: 444: 44.51
+	Hs
		623266 ACTS_HUMAN (2-376): 0: 598: 98.13		RO52_HUMAN (1-485): 1.6e-152: 444: 44.51
+	Hs
		623244 ACTA_HUMAN (1-376): 0: 595: 99.20		RO52_HUMAN (1-485): 1.6e-152: 444: 44.51
+	Hs
		952965 ACTB_HUMAN (1-376): 0: 601: 93.35		TRI58_HUMAN (1-487): 4.76e-135: 400: 36.61
+	Hs
		953081 ACTB_HUMAN (1-376): 0: 601: 93.35		TRI15_HUMAN (2-483): 1.84e-105: 324: 25.41
+	Hs
		952786 ACTB_HUMAN (1-376): 0: 601: 93.35		TRI26_HUMAN (2-364): 7.66e-48: 174: 32.99