HitPredict

Interactor 1: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Interactor 2: TRIM6 (Q9C030)
Tripartite motif-containing protein 6 (EC 2.3.2.27) (RING finger protein 89) (RING-type E3 ubiquitin transferase TRIM6)
Gene: TRIM6

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	38515377
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019901 - protein kinase binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 375 Hs			1 488
+	Hs
		623371 ACTBL_HUMAN (2-375): 0: 735: 91.71		RO52_HUMAN (1-485): 1.6e-152: 444: 44.51
+	Hs
		1247488 POTEE_HUMAN (1-375): 0: 736: 92.00		TRI72_HUMAN (3-487): 4.46e-103: 318: 23.23
+	Hs
		996531 ACTS_HUMAN (2-375): 0: 592: 93.58		TRIM6_HUMAN (1-488): 2.05e-158: 460: 100.00
+	Hs
		993443 ACTH_HUMAN (2-375): 0: 589: 93.58		TRIM6_HUMAN (1-488): 2.05e-158: 460: 100.00
+	Hs
		623217 ACTB_HUMAN (1-375): 0: 603: 100.00		RO52_HUMAN (1-485): 1.6e-152: 444: 44.51
+	Hs
		623263 ACTG_HUMAN (1-375): 0: 601: 98.93		RO52_HUMAN (1-485): 1.6e-152: 444: 44.51
+	Hs
		623266 ACTS_HUMAN (2-375): 0: 592: 93.58		RO52_HUMAN (1-485): 1.6e-152: 444: 44.51
+	Hs
		623244 ACTA_HUMAN (2-375): 0: 591: 94.12		RO52_HUMAN (1-485): 1.6e-152: 444: 44.51
+	Hs
		952965 ACTB_HUMAN (1-375): 0: 603: 100.00		TRI58_HUMAN (1-487): 4.76e-135: 400: 36.61
+	Hs
		953081 ACTB_HUMAN (1-375): 0: 603: 100.00		TRI15_HUMAN (2-483): 1.84e-105: 324: 25.41
+	Hs
		952786 ACTB_HUMAN (1-375): 0: 603: 100.00		TRI26_HUMAN (2-364): 7.66e-48: 174: 32.99