HitPredict

Interactor 1: UBC9 (P63280)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (mUBC9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I)
Gene: Ube2i

Interactor 2: NR2C1 (Q505F1)
Nuclear receptor subfamily 2 group C member 1 (Orphan nuclear receptor TR2) (Testicular receptor 2) (mTR2)
Gene: NR2C1

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.573

Property	Details
Experiments	17187077
Identification Methods	anti bait coimmunoprecipitation, two hybrid, pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016605 - PML body
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 158 Mm			1 590
+	Hs
		878865 UB2D3_HUMAN (4-157): 7.34e-73: 216: 35.07		NR2C2_HUMAN (15-590): 1.43e-151: 450: 58.45
+	Hs
		878810 UB2E1_HUMAN (3-156): 1.02e-66: 202: 33.12		NR2C2_HUMAN (15-590): 1.43e-151: 450: 58.45
+	Hs
		137532 UBC9_HUMAN (1-158): 1.96e-70: 211: 100.00		NR5A2_HUMAN (19-579): 2.77e-111: 345: 21.95
+	Hs
		993604 UBC9_HUMAN (1-158): 1.96e-70: 211: 100.00		Q58EY0_HUMAN (94-577): 3.89e-92: 292: 20.29
+	Hs
		993544 UBC9_HUMAN (1-158): 1.96e-70: 211: 100.00		STF1_HUMAN (94-579): 3.35e-87: 280: 21.01
+	Hs
		282933 UBC9_HUMAN (1-158): 1.96e-70: 211: 100.00		NR1I2_HUMAN (78-574): 5.79e-79: 257: 17.46
+	Hs
		625795 UBC9_HUMAN (1-158): 1.96e-70: 211: 100.00		RXRA_HUMAN (23-240): 5.89e-52: 186: 27.12
+	Hs
		833913 UBC9_HUMAN (1-158): 1.96e-70: 211: 100.00		HNF4A_HUMAN (72-209): 4.8e-44: 165: 39.13