HitPredict

Interactor 1: EF1A1 (P68104)
Elongation factor 1-alpha 1 (EF-1-alpha-1) (EC 3.6.5.-) (Elongation factor Tu) (EF-Tu) (Eukaryotic elongation factor 1 A-1) (eEF1A-1) (Leukocyte receptor cluster member 7)
Gene: EEF1A1

Interactor 2: CDK12 (Q9NYV4)
Cyclin-dependent kinase 12 (EC 2.7.11.22) (EC 2.7.11.23) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) (Cell division cycle 2-related protein kinase 7) (CDC2-related protein kinase 7) (Cell division protein kinase 12) (hCDK12)
Gene: CDK12

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34349018
Identification Methods	cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0019901 - protein kinase binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 462 Hs			1 1490
+	Hs
		667756 EF1A1_HUMAN (1-462): 0: 578: 100.00		CDK2_HUMAN (724-1026): 2.26e-140: 434: 41.12
+	Hs
		1025254 EF1A2_HUMAN (1-461): 0: 568: 92.63		CDK3_HUMAN (724-1028): 1.71e-139: 432: 42.48
+	Hs
		897729 EF1A1_HUMAN (1-462): 0: 578: 100.00		CDK9_HUMAN (724-1079): 1.52e-124: 394: 42.90
+	Hs
		897759 EF1A2_HUMAN (1-461): 0: 568: 92.63		CDK9_HUMAN (724-1079): 1.52e-124: 394: 42.90
+	Sc
		394876 EF1A_YEAST (1-445): 0: 539: 80.90		CTK1_YEAST (733-1056): 2.56e-73: 256: 45.73