HitPredict

Interactor 1: CDK9 (P50750)
Cyclin-dependent kinase 9 (EC 2.7.11.22) (EC 2.7.11.23) (C-2K) (Cell division cycle 2-like protein kinase 4) (Cell division protein kinase 9) (Serine/threonine-protein kinase PITALRE) (Tat-associated kinase complex catalytic subunit)
Gene: CDK9

Interactor 2: EF1A1 (P68104)
Elongation factor 1-alpha 1 (EF-1-alpha-1) (EC 3.6.5.-) (Elongation factor Tu) (EF-Tu) (Eukaryotic elongation factor 1 A-1) (eEF1A-1) (Leukocyte receptor cluster member 7)
Gene: EEF1A1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	27684187, 26209609
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0016020 - membrane GO:0019901 - protein kinase binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 372 Hs			1 462
+	Hs
		897759 CDK9_HUMAN (1-372): 1.49e-148: 426: 100.00		EF1A2_HUMAN (1-461): 0: 568: 92.63
+	Hs
		667756 CDK2_HUMAN (16-321): 3.19e-137: 394: 38.76		EF1A1_HUMAN (1-462): 0: 578: 100.00
+	Hs
		996370 CDK12_HUMAN (16-371): 2.05e-123: 390: 42.54		EF1A1_HUMAN (1-462): 0: 578: 100.00
+	Rn
		639958 MK03_RAT (9-362): 7.01e-132: 384: 30.79		EF1A1_RAT (1-462): 0: 578: 99.78
+	Hs
		1025254 CDK3_HUMAN (16-332): 1.77e-135: 390: 37.11		EF1A2_HUMAN (1-461): 0: 568: 92.63
+	Rn
		639959 MK03_RAT (9-362): 7.01e-132: 384: 30.79		EF1A2_RAT (1-461): 0: 567: 92.63
+	Sc
		394876 CTK1_YEAST (17-331): 3.27e-72: 235: 39.25		EF1A_YEAST (1-445): 0: 539: 80.90
+	Sc
		394253 BUR1_YEAST (19-323): 6.5e-69: 230: 41.30		EF1A_YEAST (1-445): 0: 539: 80.90