HitPredict

Interactor 1: SSRP1 (Q08945)
FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160)
Gene: SSRP1

Interactor 2: SMRC1 (Q92922)
SWI/SNF complex subunit SMARCC1 (BRG1-associated factor 155) (BAF155) (SWI/SNF complex 155 kDa subunit) (SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1)
Gene: SMARCC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006337 - nucleosome disassembly GO:0042393 - histone binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 709 Hs			1 1105
+	Hs
		1272921 CIC_HUMAN (424-708): 7.87e-39: 157: 16.49		SMRC1_HUMAN (30-1074): 0: 1148: 100.00
+	Hs
		818829 SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15		SMRC1_HUMAN (30-1074): 0: 1148: 100.00
+	Hs
		818822 SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15		SMRC2_HUMAN (32-1105): 0: 956: 57.71
+	Hs
		261483 SSRP1_HUMAN (1-709): 0: 805: 100.00		NCOR1_HUMAN (619-1062): 6.7e-30: 131: 11.55
+	Hs
		996631 SSRP1_HUMAN (1-709): 0: 805: 100.00		EP300_HUMAN (769-1082): 7e-28: 124: 13.19
+	Sc
		797945 POB3_YEAST (4-504): 0: 541: 29.66		RSC8_YEAST (367-850): 1.21e-111: 360: 25.49
+	Sc
		696149 RT106_YEAST (337-544): 3.23e-31: 129: 17.37		SWI3_YEAST (288-849): 1.51e-109: 363: 24.72
+	Sc
		770089 RT106_YEAST (337-544): 3.23e-31: 129: 17.37		RSC8_YEAST (367-850): 1.21e-111: 360: 25.49
+	Hs
		881837 SOX10_HUMAN (444-707): 4.49e-36: 143: 14.93		NCOR2_HUMAN (614-1100): 2.99e-44: 177: 15.22
+	Hs
		727951 SOX6_HUMAN (449-700): 3.73e-33: 138: 14.96		NCOR2_HUMAN (614-1100): 2.99e-44: 177: 15.22
+	Hs
		1332335 SOX17_HUMAN (475-708): 1.45e-32: 132: 12.61		NCOR2_HUMAN (614-1100): 2.99e-44: 177: 15.22
+	Hs
		225812 SOX15_HUMAN (513-702): 2.03e-33: 130: 15.10		NCOR2_HUMAN (614-1100): 2.99e-44: 177: 15.22
+	Hs
		261453 SOX10_HUMAN (444-707): 4.49e-36: 143: 14.93		NCOR1_HUMAN (619-1062): 6.7e-30: 131: 11.55
+	Hs
		261422 SOX6_HUMAN (449-700): 3.73e-33: 138: 14.96		NCOR1_HUMAN (619-1062): 6.7e-30: 131: 11.55
+	Hs
		881798 SOX10_HUMAN (444-707): 4.49e-36: 143: 14.93		EP300_HUMAN (769-1082): 7e-28: 124: 13.19
+	Hs
		818793 SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15		EP300_HUMAN (769-1082): 7e-28: 124: 13.19
+	Hs
		261591 SOX17_HUMAN (475-708): 1.45e-32: 132: 12.61		NCOR1_HUMAN (619-1062): 6.7e-30: 131: 11.55
+	Hs
		225734 SOX15_HUMAN (513-702): 2.03e-33: 130: 15.10		EP300_HUMAN (769-1082): 7e-28: 124: 13.19
+	Hs
		818819 SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15		KMT2C_HUMAN (664-1105): 1.43e-09: 65: 7.64
+	Hs
		1243843 SOX17_HUMAN (475-708): 1.45e-32: 132: 12.61		KMT2C_HUMAN (664-1105): 1.43e-09: 65: 7.64