HitPredict

Interactor 1: SSRP1 (Q08945)
FACT complex subunit SSRP1 (Chromatin-specific transcription elongation factor 80 kDa subunit) (Facilitates chromatin transcription complex 80 kDa subunit) (FACT 80 kDa subunit) (FACTp80) (Facilitates chromatin transcription complex subunit SSRP1) (Recombination signal sequence recognition protein 1) (Structure-specific recognition protein 1) (hSSRP1) (T160)
Gene: SSRP1

Interactor 2: SNR40 (Q96DI7)
U5 small nuclear ribonucleoprotein 40 kDa protein (U5 snRNP 40 kDa protein) (U5-40K) (38 kDa-splicing factor) (Prp8-binding protein) (hPRP8BP) (U5 snRNP-specific 40 kDa protein) (WD repeat-containing protein 57)
Gene: SNRNP40

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35271311, 37689310
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 709 Hs			1 357
+	Hs
		903169 SSRP1_HUMAN (1-709): 0: 805: 100.00		WDR5_HUMAN (95-357): 1.45e-83: 258: 25.09
+	Hs
		996930 SSRP1_HUMAN (1-709): 0: 805: 100.00		NLE1_HUMAN (2-312): 5.34e-81: 256: 21.45
+	Hs
		996881 SSRP1_HUMAN (1-709): 0: 805: 100.00		TBL1R_HUMAN (2-183): 1.23e-48: 172: 24.61
+	Hs
		245594 SSRP1_HUMAN (1-709): 0: 805: 100.00		TBL1X_HUMAN (173-357): 9.69e-31: 124: 16.18
+	Hs
		996813 SSRP1_HUMAN (1-709): 0: 805: 100.00		FBXW7_HUMAN (53-216): 6.52e-28: 116: 27.17
+	Hs
		903450 CIC_HUMAN (424-708): 7.87e-39: 157: 16.49		WDR5_HUMAN (95-357): 1.45e-83: 258: 25.09
+	Hs
		817868 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		WDR5_HUMAN (95-357): 1.45e-83: 258: 25.09
+	Ce
		1089274 SOX2_CAEEL (503-706): 2.71e-35: 137: 15.46		WDR51_CAEEL (1-262): 4.45e-72: 230: 23.42
+	Hs
		1288324 HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20		SNR40_HUMAN (143-357): 1.07e-57: 192: 19.73
+	Hs
		869834 PMS1_HUMAN (400-704): 7.54e-34: 141: 16.23		SNR40_HUMAN (143-357): 1.07e-57: 192: 19.73
+	Hs
		818441 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		TBL1R_HUMAN (2-183): 1.23e-48: 172: 24.61
+	Hs
		1281404 HM20A_HUMAN (460-709): 1.81e-42: 159: 17.20		FBXW7_HUMAN (53-216): 6.52e-28: 116: 27.17
+	Hs
		245585 SOX10_HUMAN (444-707): 4.49e-36: 143: 14.93		TBL1X_HUMAN (173-357): 9.69e-31: 124: 16.18
+	Hs
		245570 SOX6_HUMAN (449-700): 3.73e-33: 138: 14.96		TBL1X_HUMAN (173-357): 9.69e-31: 124: 16.18
+	Hs
		881823 SOX10_HUMAN (444-707): 4.49e-36: 143: 14.93		FBXW7_HUMAN (53-216): 6.52e-28: 116: 27.17
+	Hs
		245636 SOX17_HUMAN (475-708): 1.45e-32: 132: 12.61		TBL1X_HUMAN (173-357): 9.69e-31: 124: 16.18
+	Hs
		818834 SOX9_HUMAN (447-703): 1.35e-34: 140: 15.15		FBXW7_HUMAN (53-216): 6.52e-28: 116: 27.17
+	Hs
		245569 SOX5_HUMAN (441-648): 2.62e-30: 129: 19.23		TBL1X_HUMAN (173-357): 9.69e-31: 124: 16.18
+	Hs
		245575 SOX2_HUMAN (516-636): 8.67e-30: 122: 22.31		TBL1X_HUMAN (173-357): 9.69e-31: 124: 16.18
+	Mm
		57650 A2AWT7_MOUSE (355-708): 5.83e-25: 112: 10.61		A16L1_MOUSE (41-350): 2.91e-34: 134: 29.56