Download interactions: TXT MITAB-2.5
| Interaction | Interactor | Experiments | Homologs | Category | Interaction Score |
Confidence |
|---|---|---|---|---|---|---|
|
MYD88
Myeloid differentiation primary response protein MyD88 |
19 |
20 |
Small-scale |
0.989 | High |
|
|
IRAK1
Interleukin-1 receptor-associated kinase 1 |
22 |
20 |
Small-scale |
0.988 | High |
|
|
TIRAP
Toll/interleukin-1 receptor domain-containing adapter protein |
14 |
6 |
Small-scale |
0.984 | High |
|
|
IRAK2
Interleukin-1 receptor-associated kinase-like 2 |
4 |
20 |
Small-scale |
0.896 | High |
|
|
FADD
FAS-associated death domain protein |
3 |
7 |
Small-scale |
0.829 | High |
|
|
SARM1
NAD(+) hydrolase SARM1 |
2 |
2 |
Small-scale |
0.800 | High |
|
|
IRAK3
Interleukin-1 receptor-associated kinase 3 |
2 |
20 |
Small-scale |
0.776 | High |
|
|
IRAK4
Interleukin-1 receptor-associated kinase 4 |
21 |
10 |
Small-scale |
0.767 | High |
|
|
TLR4
Toll-like receptor 4 |
15 |
18 |
Small-scale |
0.761 | High |
|
|
SPOP
Speckle-type POZ protein |
9 |
6 |
Small-scale |
0.757 | High |
|
|
IL1R1
Interleukin-1 receptor type 1 |
11 |
13 |
Small-scale |
0.752 | High |
|
|
TLR2
Toll-like receptor 2 |
7 |
16 |
Small-scale |
0.743 | High |
|
|
TRAF6
TNF receptor-associated factor 6 |
7 |
19 |
Small-scale |
0.739 | High |
|
|
IRF7
Interferon regulatory factor 7 |
4 |
20 |
Small-scale |
0.701 | High |
|
|
TLR5
Toll-like receptor 5 |
5 |
20 |
Small-scale |
0.701 | High |
|
|
TLR9
Toll-like receptor 9 |
3 |
20 |
Small-scale |
0.650 | High |
|
|
HDAC6
Protein deacetylase HDAC6 |
3 |
1 |
Small-scale |
0.650 | High |
|
|
IL1AP
Interleukin-1 receptor accessory protein |
3 |
20 |
Small-scale |
0.640 | High |
|
|
SIAH1
E3 ubiquitin-protein ligase SIAH1 |
2 |
7 |
Small-scale |
0.631 | High |
|
|
IRF5
Interferon regulatory factor 5 |
2 |
20 |
Small-scale |
0.624 | High |
|
|
TNR16
Tumor necrosis factor receptor superfamily member 16 |
1 |
1 |
Small-scale |
0.618 | High |
|
|
TCAM2
TIR domain-containing adapter molecule 2 |
1 |
12 |
Small-scale |
0.618 | High |
|
|
SPOPL
Speckle-type POZ protein-like |
2 |
6 |
High-throughput |
0.606 | High |
|
|
TR13B
Tumor necrosis factor receptor superfamily member 13B |
1 |
1 |
Small-scale |
0.604 | High |
|
|
IRF4
Interferon regulatory factor 4 |
2 |
20 |
Small-scale |
0.601 | High |
|
|
MAL
Myelin and lymphocyte protein |
2 |
1 |
Small-scale |
0.586 | High |
|
|
KSYK
Tyrosine-protein kinase SYK |
2 |
18 |
Small-scale |
0.584 | High |
|
|
CBLB
E3 ubiquitin-protein ligase CBL-B |
2 |
2 |
Small-scale |
0.584 | High |
|
|
TNIP1
TNFAIP3-interacting protein 1 |
2 |
2 |
Small-scale |
0.584 | High |
|
|
SIGIR
Single Ig IL-1-related receptor |
2 |
15 |
Small-scale |
0.584 | High |
|
|
ZNF35
Zinc finger protein 35 |
2 |
0 |
High-throughput |
0.580 | High |
|
|
RNF4
E3 ubiquitin-protein ligase RNF4 |
2 |
0 |
High-throughput |
0.580 | High |
|
|
NTAQ1
Protein N-terminal glutamine amidohydrolase |
2 |
0 |
High-throughput |
0.580 | High |
|
|
RAC1
Ras-related C3 botulinum toxin substrate 1 |
1 |
4 |
Small-scale |
0.578 | High |
|
|
TLR7
Toll-like receptor 7 |
2 |
20 |
Small-scale |
0.576 | High |
|
|
SMAD3
Mothers against decapentaplegic homolog 3 |
1 |
4 |
High-throughput |
0.573 | High |
|
|
UBP7
Ubiquitin carboxyl-terminal hydrolase 7 |
1 |
1 |
High-throughput |
0.573 | High |
|
|
THIO
Thioredoxin |
1 |
0 |
High-throughput |
0.561 | High |
|
|
RN152
E3 ubiquitin-protein ligase RNF152 |
1 |
3 |
Small-scale |
0.561 | High |
|
|
STAP2
Signal-transducing adaptor protein 2 |
1 |
0 |
Small-scale |
0.554 | High |
|
|
CISH
Cytokine-inducible SH2-containing protein |
1 |
18 |
Small-scale |
0.552 | High |
|
|
RAGE
Advanced glycosylation end product-specific receptor |
1 |
4 |
Small-scale |
0.536 | High |
|
|
LRRF2
Leucine-rich repeat flightless-interacting protein 2 |
2 |
4 |
Small-scale |
0.533 | High |
|
|
PFKAL
ATP-dependent 6-phosphofructokinase, liver type |
1 |
0 |
High-throughput |
0.518 | High |
|
|
MDM2
E3 ubiquitin-protein ligase Mdm2 |
1 |
0 |
High-throughput |
0.518 | High |
|
|
PRDX1
Peroxiredoxin-1 |
1 |
0 |
High-throughput |
0.518 | High |
|
|
MBIP1
MAP3K12-binding inhibitory protein 1 |
1 |
0 |
High-throughput |
0.518 | High |
|
|
IRF1
Interferon regulatory factor 1 |
1 |
20 |
Small-scale |
0.515 | High |
|
|
ILRL1
Interleukin-1 receptor-like 1 |
1 |
13 |
Small-scale |
0.515 | High |
|
|
BTK
Tyrosine-protein kinase BTK |
1 |
15 |
Small-scale |
0.515 | High |
|
|
PELI1
E3 ubiquitin-protein ligase pellino homolog 1 |
1 |
2 |
Small-scale |
0.515 | High |
|
|
Q69FE3
Interleukin-1 receptor-associated kinase 4 |
1 |
10 |
High-throughput |
0.515 | High |
|
|
DOCK8
Dedicator of cytokinesis protein 8 |
1 |
0 |
Small-scale |
0.513 | High |
|
|
CYH2
Cytohesin-2 |
1 |
0 |
Small-scale |
0.512 | High |
|
|
TLR1
Toll-like receptor 1 |
1 |
17 |
Small-scale |
0.506 | High |
|
|
TLR6
Toll-like receptor 6 |
1 |
20 |
Small-scale |
0.506 | High |
|
|
TLR3
Toll-like receptor 3 |
1 |
20 |
Small-scale |
0.501 | High |
|
|
NEMO
NF-kappa-B essential modulator |
1 |
3 |
Small-scale |
0.501 | High |
|
|
SIAH2
E3 ubiquitin-protein ligase SIAH2 |
1 |
19 |
High-throughput |
0.481 | High |
|
|
C1QR1
Complement component C1q receptor |
1 |
4 |
High-throughput |
0.481 | High |
|
|
SMAD6
Mothers against decapentaplegic homolog 6 |
1 |
4 |
Small-scale |
0.479 | High |
|
|
TBB5
Tubulin beta chain |
1 |
7 |
Small-scale |
0.479 | High |
|
|
HS90A
Heat shock protein HSP 90-alpha |
1 |
4 |
Small-scale |
0.479 | High |
|
|
HSP7C
Heat shock cognate 71 kDa protein |
1 |
6 |
Small-scale |
0.479 | High |
|
|
HSP76
Heat shock 70 kDa protein 6 |
1 |
6 |
Small-scale |
0.479 | High |
|
|
EGR1
Early growth response protein 1 |
1 |
2 |
High-throughput |
0.479 | High |
|
|
P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha |
1 |
8 |
Small-scale |
0.479 | High |
|
|
HS71L
Heat shock 70 kDa protein 1-like |
1 |
6 |
Small-scale |
0.479 | High |
|
|
BCL6
B-cell lymphoma 6 protein |
1 |
2 |
Small-scale |
0.479 | High |
|
|
TCPQ
T-complex protein 1 subunit theta |
1 |
3 |
Small-scale |
0.479 | High |
|
|
TCPD
T-complex protein 1 subunit delta |
1 |
2 |
Small-scale |
0.479 | High |
|
|
TBA1B
Tubulin alpha-1B chain |
1 |
8 |
Small-scale |
0.479 | High |
|
|
TCPB
T-complex protein 1 subunit beta |
1 |
2 |
Small-scale |
0.479 | High |
|
|
FLII
Protein flightless-1 homolog |
1 |
1 |
Small-scale |
0.479 | High |
|
|
TRAF3
TNF receptor-associated factor 3 |
1 |
20 |
Small-scale |
0.479 | High |
|
|
TIF1B
Transcription intermediary factor 1-beta |
1 |
3 |
High-throughput |
0.479 | High |
|
|
SQSTM
Sequestosome-1 |
1 |
2 |
Small-scale |
0.479 | High |
|
|
IKKE
Inhibitor of nuclear factor kappa-B kinase subunit epsilon |
1 |
6 |
Small-scale |
0.479 | High |
|
|
FAK2
Protein-tyrosine kinase 2-beta |
1 |
7 |
Small-scale |
0.479 | High |
|
|
IRF3
Interferon regulatory factor 3 |
1 |
20 |
Small-scale |
0.479 | High |
|
|
TRIP6
Thyroid receptor-interacting protein 6 |
1 |
1 |
Small-scale |
0.479 | High |
|
|
LRRF1
Leucine-rich repeat flightless-interacting protein 1 |
1 |
3 |
Small-scale |
0.479 | High |
|
|
TRI67
Tripartite motif-containing protein 67 |
1 |
4 |
High-throughput |
0.479 | High |
|
|
BCAP
Phosphoinositide 3-kinase adapter protein 1 |
1 |
6 |
Small-scale |
0.479 | High |
|
|
TBA1A
Tubulin alpha-1A chain |
1 |
8 |
Small-scale |
0.479 | High |
|
|
BANK1
B-cell scaffold protein with ankyrin repeats |
1 |
6 |
Small-scale |
0.479 | High |
|
|
TCPH
T-complex protein 1 subunit eta |
1 |
2 |
Small-scale |
0.479 | High |
|
|
TLR10
Toll-like receptor 10 |
1 |
20 |
Small-scale |
0.479 | High |
|
|
PKHA4
Pleckstrin homology domain-containing family A member 4 |
1 |
1 |
High-throughput |
0.479 | High |
|
|
ILRL2
Interleukin-1 receptor-like 2 |
1 |
19 |
Small-scale |
0.479 | High |
|
|
ZRAN1
Ubiquitin thioesterase ZRANB1 |
1 |
2 |
High-throughput |
0.479 | High |
|
|
RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1 |
1 |
0 |
High-throughput |
0.460 | High |
|
|
R113A
E3 ubiquitin-protein ligase RNF113A |
1 |
0 |
High-throughput |
0.458 | High |
|
|
SASH1
SAM and SH3 domain-containing protein 1 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain] |
1 |
0 |
High-throughput |
0.458 | High |
|
|
DDX6
Probable ATP-dependent RNA helicase DDX6 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
1433E
14-3-3 protein epsilon |
1 |
0 |
Small-scale |
0.458 | High |
|
|
BST2
Bone marrow stromal antigen 2 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
SF3A3
Splicing factor 3A subunit 3 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
PARPT
Protein mono-ADP-ribosyltransferase TIPARP |
1 |
0 |
High-throughput |
0.458 | High |
|
|
ATX2L
Ataxin-2-like protein |
1 |
0 |
Small-scale |
0.458 | High |
|
|
TS101
Tumor susceptibility gene 101 protein |
1 |
0 |
Small-scale |
0.458 | High |
|
|
ATG5
Autophagy protein 5 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
SMUF1
E3 ubiquitin-protein ligase SMURF1 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
CYLD
Ubiquitin carboxyl-terminal hydrolase CYLD |
1 |
0 |
Small-scale |
0.458 | High |
|
|
UBAP1
Ubiquitin-associated protein 1 |
1 |
0 |
Small-scale |
0.458 | High |
|
|
SUFU
Suppressor of fused homolog |
1 |
0 |
Small-scale |
0.458 | High |
|
|
TLR8
Toll-like receptor 8 |
1 |
20 |
Small-scale |
0.457 | High |
|
|
IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta |
1 |
6 |
Small-scale |
0.445 | High |
|
|
ARMX6
Protein ARMCX6 |
1 |
0 |
High-throughput |
0.279 | Low |
|
|
GLOD4
Glyoxalase domain-containing protein 4 |
1 |
0 |
High-throughput |
0.279 | Low |
Service provided by Combinatics, Japan
Last updated: 11Aug2025
