HitPredict

Interactor 1: TBB4B (P68371)
Tubulin beta-4B chain (Tubulin beta-2 chain) (Tubulin beta-2C chain)
Gene: TUBB4B

Interactor 2: AGO3 (Q9H9G7)
Protein argonaute-3 (Argonaute3) (hAgo3) (EC 3.1.26.n2) (Argonaute RISC catalytic component 3) (Eukaryotic translation initiation factor 2C 3) (eIF-2C 3) (eIF2C 3)
Gene: AGO3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	19167051
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003725 - double-stranded RNA binding GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0046872 - metal ion binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 445 Hs			1 860
+	Hs
		457708 TBB5_HUMAN (1-429): 0: 711: 98.37		AGO3_HUMAN (1-860): 0: 1185: 100.00
+	Hs
		1118601 TBB2A_HUMAN (1-430): 0: 707: 97.67		AGO3_HUMAN (1-860): 0: 1185: 100.00
+	Hs
		408169 TBB4A_HUMAN (1-427): 0: 706: 98.60		AGO3_HUMAN (1-860): 0: 1185: 100.00
+	Hs
		457721 TBB5_HUMAN (1-429): 0: 711: 98.37		AGO4_HUMAN (3-860): 0: 1114: 80.81
+	Hs
		997524 TBB4B_HUMAN (1-427): 0: 711: 100.00		AGO4_HUMAN (3-860): 0: 1114: 80.81
+	Hs
		1192004 TBB8_HUMAN (1-427): 0: 696: 91.10		AGO2_HUMAN (15-860): 0: 1127: 80.73
+	Hs
		1108667 TBB3_HUMAN (1-443): 0: 714: 93.23		PIWL1_HUMAN (9-827): 0: 729: 21.57