HitPredict

Interactor 1: RBBP4 (Q09028)
Histone-binding protein RBBP4 (Chromatin assembly factor 1 subunit C) (CAF-1 subunit C) (Chromatin assembly factor I p48 subunit) (CAF-I 48 kDa subunit) (CAF-I p48) (Nucleosome-remodeling factor subunit RBAP48) (Retinoblastoma-binding protein 4) (RBBP-4) (Retinoblastoma-binding protein p48)
Gene: RBBP4

Interactor 2: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32235678, 17079684
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 425 Hs			1 759
+	Hs
		1043016 RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		997715 RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		1043376 RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		1043085 WDR5B_HUMAN (92-417): 1.53e-68: 222: 18.54		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		997713 RBBP4_HUMAN (1-425): 4.3e-124: 367: 100.00		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		1041672 RBBP7_HUMAN (1-425): 3.63e-115: 345: 89.20		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		1043441 WDR5B_HUMAN (92-417): 1.53e-68: 222: 18.54		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		1043114 POC1B_HUMAN (2-229): 2.56e-47: 170: 12.45		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		1043562 TBL1R_HUMAN (109-424): 2.86e-60: 205: 16.52		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		1043469 POC1B_HUMAN (2-229): 2.56e-47: 170: 12.45		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		903208 WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61		CUL4A_HUMAN (1-759): 0: 963: 100.00
+	Hs
		245601 TBL1X_HUMAN (207-424): 3.72e-35: 138: 17.63		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		903209 WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61		CUL4B_HUMAN (10-759): 0: 927: 82.31
+	Hs
		1041647 TAF5_HUMAN (153-417): 2.83e-46: 172: 15.23		CUL3_HUMAN (32-759): 0: 814: 38.23
+	At
		186930 MSI1_ARATH (2-210): 3.43e-31: 125: 13.22		CUL4_ARATH (24-759): 0: 861: 57.40
+	Hs
		1042101 POC1B_HUMAN (2-229): 2.56e-47: 170: 12.45		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		903207 WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		1042394 GRWD1_HUMAN (263-425): 3.54e-26: 111: 23.56		CUL3_HUMAN (32-759): 0: 814: 38.23
+	Hs
		903206 WDR5_HUMAN (267-425): 7.48e-35: 133: 25.61		CUL1_HUMAN (59-759): 0: 745: 30.55
+	Hs
		1041172 GRWD1_HUMAN (263-425): 3.54e-26: 111: 23.56		CUL1_HUMAN (59-759): 0: 745: 30.55