HitPredict

Interactor 1: BRO1 (F4HXZ1)
Vacuolar-sorting protein BRO1 (BRO domain-containing protein 1) (AtBRO1)
Gene: BRO1

Interactor 2: VP322 (Q9SZE4)
Vacuolar protein sorting-associated protein 32 homolog 2 (AtVPS32-2) (Charged multivesicular body protein 4 homolog 2) (ESCRT-III complex subunit VPS32 homolog 2)
Gene: VPS32.2

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.559

Property	Details
Experiments	22639582, 21798944
Identification Methods	two hybrid, two hybrid array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 846 At			1 219
+	At
		99780 BRO1_ARATH (1-846): 3.04e-180: 541: 100.00		VP321_ARATH (1-219): 1.39e-38: 134: 79.91
+	Hs
		1356974 PDC6I_HUMAN (10-846): 7.66e-154: 474: 24.43		CHM4C_HUMAN (8-218): 4.63e-41: 141: 33.79
+	Dm
		1345393 Q9VB05_DROME (10-846): 1.06e-152: 470: 25.44		CHM4_DROME (1-218): 1.47e-42: 144: 28.38
+	Hs
		1357001 PDC6I_HUMAN (10-846): 7.66e-154: 474: 24.43		CHM4B_HUMAN (13-218): 7.5e-40: 137: 37.86
+	Hs
		1356990 PDC6I_HUMAN (10-846): 7.66e-154: 474: 24.43		CHM4A_HUMAN (2-217): 7.65e-36: 127: 35.32
+	Hs
		1432897 PTN23_HUMAN (9-842): 1.85e-141: 459: 22.76		CHM4B_HUMAN (13-218): 7.5e-40: 137: 37.86
+	Dm
		1345403 Q9VUH6_DROME (10-845): 1.27e-105: 360: 21.26		CHM4_DROME (1-218): 1.47e-42: 144: 28.38
+	Sc
		815035 BRO1_YEAST (10-809): 8.09e-95: 317: 18.04		SNF7_YEAST (1-208): 1.64e-34: 124: 27.70
+	Sc
		874379 BRO1_YEAST (10-809): 8.09e-95: 317: 18.04		VPS20_YEAST (8-219): 5.7e-33: 120: 17.97
+	Sc
		815076 PALA_YEAST (10-719): 3.8e-93: 308: 20.86		SNF7_YEAST (1-208): 1.64e-34: 124: 27.70
+	Hs
		1218794 BROX_HUMAN (26-357): 1.5e-64: 224: 18.70		CHM4C_HUMAN (8-218): 4.63e-41: 141: 33.79
+	Hs
		1218797 BROX_HUMAN (26-357): 1.5e-64: 224: 18.70		CHM4B_HUMAN (13-218): 7.5e-40: 137: 37.86
+	Hs
		1218801 BROX_HUMAN (26-357): 1.5e-64: 224: 18.70		CHMP5_HUMAN (2-193): 2.87e-36: 128: 30.20
+	Hs
		1218796 BROX_HUMAN (26-357): 1.5e-64: 224: 18.70		CHM4A_HUMAN (2-217): 7.65e-36: 127: 35.32