HitPredict

Interactor 1: NCBP1 (Q09161)
Nuclear cap-binding protein subunit 1 (80 kDa nuclear cap-binding protein) (CBP80) (NCBP 80 kDa subunit)
Gene: NCBP1

Interactor 2: SRSF9 (Q13242)
Serine/arginine-rich splicing factor 9 (Pre-mRNA-splicing factor SRp30C) (Splicing factor, arginine/serine-rich 9)
Gene: SRSF9

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	1.00	0.737

Property	Details
Experiments	17643375, 32960270
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	MIF4G_like~RRM_1, MIF4G_like_2~RRM_1
Common GO terms	GO:0000380 - alternative mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0003729 - mRNA binding GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 790 Hs			1 221
+	Hs
		992738 NCBP1_HUMAN (1-790): 0: 1180: 100.00		SRSF1_HUMAN (1-183): 1.13e-57: 184: 69.95
+	Hs
		998033 NCBP1_HUMAN (1-790): 0: 1180: 100.00		SRSF5_HUMAN (12-176): 4.58e-54: 176: 35.20
+	Hs
		998034 NCBP1_HUMAN (1-790): 0: 1180: 100.00		SRSF6_HUMAN (15-176): 1.67e-51: 171: 36.67
+	Hs
		516479 NCBP1_HUMAN (1-790): 0: 1180: 100.00		PABP1_HUMAN (12-193): 1.8e-42: 153: 20.00
+	Hs
		998037 NCBP1_HUMAN (1-790): 0: 1180: 100.00		PABP4_HUMAN (5-104): 2.37e-21: 93.4: 19.80
+	Hs
		998172 NCBP1_HUMAN (1-790): 0: 1180: 100.00		RBM4_HUMAN (110-185): 1.92e-16: 78.8: 18.42
+	Sc
		710199 NCBP1_YEAST (3-693): 2.4e-99: 329: 17.53		NOP3_YEAST (7-179): 6.54e-38: 137: 27.68
+	Sc
		376713 NCBP1_YEAST (3-693): 2.4e-99: 329: 17.53		PABP_YEAST (113-192): 2.4e-13: 70.3: 20.69