Protein: TLE2
Transducin-like enhancer protein 2 (Enhancer of split groucho-like protein 2) (ESG2)

Gene: TLE2
Organism: Homo sapiens
Interactions: 134
UniProt ID: Q04725

Gene Ontology (top 5):
GO:0003714 - transcription corepressor activity
GO:0005615 - extracellular space
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005667 - transcription regulator complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

980673

TLE3
Transducin-like enhancer protein 3

4

16

High-throughput

0.903

High

980584

TLE1
Transducin-like enhancer protein 1

4

17

Small-scale

0.902

High

980674

TLE4
Transducin-like enhancer protein 4

3

18

High-throughput

0.861

High

980679

TLE5
TLE family member 5

2

15

High-throughput

0.811

High

843166

TCPD
T-complex protein 1 subunit delta

3

20

High-throughput

0.667

High

980672

TLE2
Transducin-like enhancer protein 2

1

17

Small-scale

0.647

High

980690

DDB1
DNA damage-binding protein 1

1

9

Small-scale

0.646

High

842834

TCPQ
T-complex protein 1 subunit theta

2

20

High-throughput

0.628

High

980681

RIPP1
Protein ripply1

2

19

High-throughput

0.628

High

980689

HLX
H2.0-like homeobox protein

2

20

High-throughput

0.628

High

980695

RIPP2
Protein ripply2

2

19

High-throughput

0.628

High

150099

UTY
Histone demethylase UTY

1

19

Small-scale

0.621

High

363096

FINC
Fibronectin

1

6

High-throughput

0.618

High

631148

RS12
Small ribosomal subunit protein eS12

1

3

High-throughput

0.618

High

907861

RS16
Small ribosomal subunit protein uS9

1

5

High-throughput

0.618

High

929409

RACK1
Small ribosomal subunit protein RACK1

1

19

High-throughput

0.618

High

980693

DCAF6
DDB1- and CUL4-associated factor 6

1

19

High-throughput

0.618

High

980707

DCAF4
DDB1- and CUL4-associated factor 4

1

2

High-throughput

0.618

High

980711

DNJC7
DnaJ homolog subfamily C member 7

1

20

High-throughput

0.618

High

980715

KPCD2
Serine/threonine-protein kinase D2

1

14

High-throughput

0.618

High

980722

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

3

High-throughput

0.618

High

980726

PRP19
Pre-mRNA-processing factor 19

1

19

High-throughput

0.618

High

770798

TCPZ
T-complex protein 1 subunit zeta

3

20

High-throughput

0.609

High

826626

TCPG
T-complex protein 1 subunit gamma

3

20

High-throughput

0.609

High

943197

TCPB
T-complex protein 1 subunit beta

3

20

High-throughput

0.609

High

980712

TCPH
T-complex protein 1 subunit eta

3

20

High-throughput

0.609

High

980694

Q5JSZ1
TLE family member 4, transcriptional corepressor

1

15

High-throughput

0.575

High

150696

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

13

High-throughput

0.553

High

164860

SC16A
Protein transport protein Sec16A

1

9

High-throughput

0.553

High

980702

UBP54
Inactive ubiquitin carboxyl-terminal hydrolase 54

1

13

High-throughput

0.553

High

980717

STRN4
Striatin-4

1

19

High-throughput

0.553

High

211838

TLX3
T-cell leukemia homeobox protein 3

1

20

High-throughput

0.541

High

308075

VENTX
Homeobox protein VENTX

1

20

High-throughput

0.541

High

658626

MSX1
Homeobox protein MSX-1

1

20

High-throughput

0.541

High

724225

MSX2
Homeobox protein MSX-2

1

20

High-throughput

0.541

High

877991

FOXA3
Hepatocyte nuclear factor 3-gamma

1

20

High-throughput

0.541

High

878396

PAX9
Paired box protein Pax-9

1

20

High-throughput

0.541

High

980675

EMX2
Homeobox protein EMX2

1

20

High-throughput

0.541

High

980714

BARH1
BarH-like 1 homeobox protein

1

20

High-throughput

0.541

High

503942

HSP7C
Heat shock cognate 71 kDa protein

1

16

High-throughput

0.536

High

871537

HSP72
Heat shock-related 70 kDa protein 2

1

16

High-throughput

0.536

High

875825

MFAP4
Microfibril-associated glycoprotein 4

1

7

High-throughput

0.536

High

883096

DSCR6
Protein ripply3

1

19

High-throughput

0.536

High

980676

HME1
Homeobox protein engrailed-1

1

20

High-throughput

0.536

High

980683

CUL4B
Cullin-4B

1

20

Small-scale

0.536

High

980721

DNJB4
DnaJ homolog subfamily B member 4

1

8

High-throughput

0.536

High

980724

BAG5
BAG family molecular chaperone regulator 5

1

3

High-throughput

0.536

High

980727

CHIP
E3 ubiquitin-protein ligase CHIP

1

13

High-throughput

0.536

High

980686

HES1
Transcription factor HES-1

1

20

Small-scale

0.527

High

271754

PRDM1
PR domain zinc finger protein 1

1

6

Small-scale

0.501

High

980723

LEF1
Lymphoid enhancer-binding factor 1

1

20

Small-scale

0.501

High

323704

BAG2
BAG family molecular chaperone regulator 2

1

4

High-throughput

0.489

High

573230

TCPA
T-complex protein 1 subunit alpha

1

20

High-throughput

0.489

High

821176

TCPE
T-complex protein 1 subunit epsilon

1

20

High-throughput

0.489

High

980708

TCPW
T-complex protein 1 subunit zeta-2

1

20

High-throughput

0.489

High

980725

ANR50
Ankyrin repeat domain-containing protein 50

1

8

High-throughput

0.489

High

117670

MYO1C
Unconventional myosin-Ic

1

11

High-throughput

0.479

High

118721

AIP
AH receptor-interacting protein

1

16

High-throughput

0.479

High

181516

CLOCK
Circadian locomoter output cycles protein kaput

1

14

High-throughput

0.479

High

241745

CCD22
Coiled-coil domain-containing protein 22

1

17

High-throughput

0.479

High

323408

TTC4
Tetratricopeptide repeat protein 4

1

20

High-throughput

0.479

High

445376

RSSA
Small ribosomal subunit protein uS2

1

3

High-throughput

0.479

High

499701

CH60
60 kDa heat shock protein, mitochondrial

1

14

High-throughput

0.479

High

508956

TOP2A
DNA topoisomerase 2-alpha

1

6

High-throughput

0.479

High

538203

ENPL
Endoplasmin

1

7

High-throughput

0.479

High

559667

H12
Histone H1.2

1

9

High-throughput

0.479

High

598072

FLNA
Filamin-A

1

13

High-throughput

0.479

High

601222

VDAC1
Voltage-dependent anion-selective channel protein 1

1

3

High-throughput

0.479

High

603463

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

4

High-throughput

0.479

High

616269

RS3
Small ribosomal subunit protein uS3

1

5

High-throughput

0.479

High

681412

DNJA1
DnaJ homolog subfamily A member 1

1

9

High-throughput

0.479

High

708869

MCM7
DNA replication licensing factor MCM7

1

7

High-throughput

0.479

High

722387

RL22
Large ribosomal subunit protein eL22

1

4

High-throughput

0.479

High

773336

RL13A
Large ribosomal subunit protein uL13

1

5

High-throughput

0.479

High

783019

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

7

High-throughput

0.479

High

805643

RL27A
Large ribosomal subunit protein uL15

1

5

High-throughput

0.479

High

806829

RS9
Small ribosomal subunit protein uS4

1

5

High-throughput

0.479

High

895476

RAB10
Ras-related protein Rab-10

1

3

High-throughput

0.479

High

898603

RL26
Large ribosomal subunit protein uL24

1

4

High-throughput

0.479

High

905608

RS7
Small ribosomal subunit protein eS7

1

3

High-throughput

0.479

High

910391

RS14
Small ribosomal subunit protein uS11

1

5

High-throughput

0.479

High

911105

RS13
Small ribosomal subunit protein uS15

1

3

High-throughput

0.479

High

911351

RS11
Small ribosomal subunit protein uS17

1

5

High-throughput

0.479

High

914934

RS4X
Small ribosomal subunit protein eS4, X isoform

1

4

High-throughput

0.479

High

919364

RL23
Large ribosomal subunit protein uL14

1

1

High-throughput

0.479

High

920438

RS25
Small ribosomal subunit protein eS25

1

3

High-throughput

0.479

High

922976

RL11
Large ribosomal subunit protein uL5

1

3

High-throughput

0.479

High

929192

RS21
Small ribosomal subunit protein eS21

1

1

High-throughput

0.479

High

960756

CLH1
Clathrin heavy chain 1

1

5

High-throughput

0.479

High

966523

OTUD4
OTU domain-containing protein 4

1

5

High-throughput

0.479

High

980677

RL18
Large ribosomal subunit protein eL18

1

4

High-throughput

0.479

High

980682

CUL4A
Cullin-4A

1

20

Small-scale

0.479

High

980684

RIN1
Ras and Rab interactor 1

1

4

High-throughput

0.479

High

980685

KEAP1
Kelch-like ECH-associated protein 1

1

2

High-throughput

0.479

High

980688

MVP
Major vault protein

1

2

High-throughput

0.479

High

980696

STRP1
Striatin-interacting protein 1

1

2

High-throughput

0.479

High

980698

THOC7
THO complex subunit 7 homolog

1

1

High-throughput

0.479

High

980699

CAVN1
Caveolae-associated protein 1

1

1

High-throughput

0.479

High

980704

GCC2
GRIP and coiled-coil domain-containing protein 2

1

13

High-throughput

0.479

High

980705

CHD6
Chromodomain-helicase-DNA-binding protein 6

1

12

High-throughput

0.479

High

980706

PP4R1
Serine/threonine-protein phosphatase 4 regulatory subunit 1

1

8

High-throughput

0.479

High

980709

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

4

High-throughput

0.479

High

980710

DDX17
Probable ATP-dependent RNA helicase DDX17

1

9

High-throughput

0.479

High

980713

GNL3
Guanine nucleotide-binding protein-like 3

1

9

High-throughput

0.479

High

980720

ANFY1
Rabankyrin-5

1

7

High-throughput

0.479

High

980728

NUDC
Nuclear migration protein nudC

1

18

High-throughput

0.479

High

483787

HS71B
Heat shock 70 kDa protein 1B

1

16

High-throughput

0.445

High

166419

PUR4
Phosphoribosylformylglycinamidine synthase

1

1

High-throughput

0.437

High

171611

PFD6
Prefoldin subunit 6

1

5

High-throughput

0.437

High

243373

DNJA2
DnaJ homolog subfamily A member 2

1

9

High-throughput

0.437

High

398349

PCCB
Propionyl-CoA carboxylase beta chain, mitochondrial

1

17

High-throughput

0.437

High

541350

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

6

High-throughput

0.437

High

636898

ATPA
ATP synthase subunit alpha, mitochondrial

1

5

High-throughput

0.437

High

687197

P5CR1
Pyrroline-5-carboxylate reductase 1, mitochondrial

1

3

High-throughput

0.437

High

790243

THIM
3-ketoacyl-CoA thiolase, mitochondrial

1

5

High-throughput

0.437

High

806290

RL21
Large ribosomal subunit protein eL21

1

2

High-throughput

0.437

High

827349

EFTU
Elongation factor Tu, mitochondrial

1

5

High-throughput

0.437

High

880093

SYMC
Methionine--tRNA ligase, cytoplasmic

1

8

High-throughput

0.437

High

922808

RL32
Large ribosomal subunit protein eL32

1

1

High-throughput

0.437

High

940619

F193A
Protein FAM193A

1

1

High-throughput

0.437

High

980678

ZO1
Tight junction protein ZO-1

1

8

High-throughput

0.437

High

980680

DSC1
Desmocollin-1

1

3

High-throughput

0.437

High

980687

GANAB
Neutral alpha-glucosidase AB

1

1

High-throughput

0.437

High

980691

PCKGM
Phosphoenolpyruvate carboxykinase [GTP], mitochondrial

1

3

High-throughput

0.437

High

980692

CEP55
Centrosomal protein of 55 kDa

1

1

High-throughput

0.437

High

980697

ANR40
Ankyrin repeat domain-containing protein 40

1

2

High-throughput

0.437

High

980700

CEP85
Centrosomal protein of 85 kDa

1

20

High-throughput

0.437

High

980701

STXB4
Syntaxin-binding protein 4

1

6

High-throughput

0.437

High

980703

NUP54
Nucleoporin p54

1

6

High-throughput

0.437

High

980716

WDCP
WD repeat and coiled-coil-containing protein

1

1

High-throughput

0.437

High

980718

KIF15
Kinesin-like protein KIF15

1

3

High-throughput

0.437

High

980719

DDX18
ATP-dependent RNA helicase DDX18

1

18

High-throughput

0.437

High

58073

NBAS
NBAS subunit of NRZ tethering complex

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024