HitPredict

Interactor 1: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Interactor 2: ANM1 (Q99873)
Protein arginine N-methyltransferase 1 (EC 2.1.1.319) (Histone-arginine N-methyltransferase PRMT1) (Interferon receptor 1-bound protein 4)
Gene: PRMT1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.692

Property	Details
Experiments	28883095, 30110629, 33742100, 18280497
Identification Methods	affinity chromatography technology, enzymatic study
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:1904263 - positive regulation of TORC1 signaling
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 2414 Hs			1 371
+	Hs
		998859 EP300_HUMAN (1-2414): 0: 1113: 100.00		CARM1_HUMAN (12-361): 4.58e-117: 353: 32.80
+	Dm
		116011 M9PH39_DROME (430-2323): 0: 769: 36.52		Q9VGW7_DROME (2-371): 8.59e-163: 462: 64.79
+	Dm
		116012 M9PH39_DROME (430-2323): 0: 769: 36.52		CARM1_DROME (38-369): 8.66e-118: 353: 32.46
+	Hs
		1307086 NCOA3_HUMAN (1849-2386): 7.64e-52: 204: 21.89		ANM1_HUMAN (1-371): 0: 529: 100.00
+	Hs
		1204121 NCOA3_HUMAN (1849-2386): 7.64e-52: 204: 21.89		CARM1_HUMAN (12-361): 4.58e-117: 353: 32.80
+	Hs
		153832 TRI33_HUMAN (604-1201): 1.37e-44: 180: 14.50		ANM5_HUMAN (4-342): 4.31e-98: 306: 16.53
+	Hs
		1204062 CBP_HUMAN (1752-2400): 4.44e-10: 67.9: 13.25		CARM1_HUMAN (12-361): 4.58e-117: 353: 32.80