Protein: PARP3
Protein mono-ADP-ribosyltransferase PARP3 (EC 2.4.2.-) (ADP-ribosyltransferase diphtheria toxin-like 3) (ARTD3) (DNA ADP-ribosyltransferase PARP3) (EC 2.4.2.-) (IRT1) (NAD(+) ADP-ribosyltransferase 3) (ADPRT-3) (Poly [ADP-ribose] polymerase 3) (PARP-3) (hPARP-3) (Poly[ADP-ribose] synthase 3) (pADPRT-3)

Gene: PARP3
Organism: Homo sapiens
Interactions: 17
UniProt ID: Q9Y6F1

Gene Ontology (top 5):
GO:0000723 - telomere maintenance
GO:0003824 - catalytic activity
GO:0003950 - NAD+ poly-ADP-ribosyltransferase activity
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

487941

PARP1
Poly [ADP-ribose] polymerase 1

5

17

Small-scale

0.909

High

1258997

H32
Histone H3.2

3

13

High-throughput

0.650

High

1491836

PARP3
Protein mono-ADP-ribosyltransferase PARP3

1

16

Small-scale

0.647

High

1066256

DMWD
Dystrophia myotonica WD repeat-containing protein

1

8

High-throughput

0.536

High

1096527

PAK1
Serine/threonine-protein kinase PAK 1

1

9

High-throughput

0.536

High

769649

RFA3
Replication protein A 14 kDa subunit

1

5

High-throughput

0.515

High

1163321

H2B2E
Histone H2B type 2-E

1

18

High-throughput

0.515

High

423557

A4
Amyloid-beta precursor protein

1

4

High-throughput

0.501

High

1037459

H11
Histone H1.1

1

12

Small-scale

0.501

High

1309446

APLF
Aprataxin and PNK-like factor

1

3

Small-scale

0.501

High

1293050

RLGPB
Ral GTPase-activating protein subunit beta

1

1

High-throughput

0.489

High

894276

MEOX2
Homeobox protein MOX-2

1

5

High-throughput

0.481

High

891924

GSK3B
Glycogen synthase kinase-3 beta

1

11

Small-scale

0.479

High

1061632

FOXM1
Forkhead box protein M1

1

7

Small-scale

0.479

High

1232659

Q6FHY5
MEOX2 protein

1

5

High-throughput

0.470

High

569349

MTDC
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial [Includes: NAD-dependent methylenetetrahydrofolate dehydrogenase

1

0

High-throughput

0.269

Low


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Last updated: 11Aug2025