Interactor 1: EP300 (Q09472)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Interactor 2: BRD7 (Q9NPI1)
Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1)
Gene: BRD7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.49 1.00 0.705

The method score is based on:

Property Details
Experiments 20228809
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Bromodomain~Bromodomain, Bromodomain~RING_CBP-p300
Common GO terms GO:0000785 - chromatin
GO:0002039 - p53 binding
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
and 4 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024