Protein: 1433B
14-3-3 protein beta/alpha (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]

Gene: 1433B, Ywhab
Organism: Mus musculus
Interactions: 65
UniProt ID: Q9CQV8

Gene Ontology (top 5):
GO:0004860 - protein kinase inhibitor activity
GO:0004864 - protein phosphatase inhibitor activity
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006605 - protein targeting

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

591076

KPCE
Protein kinase C epsilon type

3

20

Small-scale

0.789

High

972307

1433E
14-3-3 protein epsilon

1

19

Small-scale

0.691

High

700377

BRAF
Serine/threonine-protein kinase B-raf

1

20

High-throughput

0.618

High

990047

1433Z
14-3-3 protein zeta/delta

1

18

High-throughput

0.618

High

1222310

KSR1
Kinase suppressor of Ras 1

1

20

Small-scale

0.618

High

1209191

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

2

20

Small-scale

0.612

High

1223711

DLG4
Disks large homolog 4

2

18

High-throughput

0.611

High

1423748

DLGP1
Disks large-associated protein 1

2

6

High-throughput

0.611

High

530905

TAU
Microtubule-associated protein tau

2

20

Small-scale

0.584

High

861895

NEDD4
E3 ubiquitin-protein ligase NEDD4

2

20

Small-scale

0.584

High

1240165

HDAC4
Histone deacetylase 4

2

20

Small-scale

0.584

High

1193917

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

2

11

High-throughput

0.558

High

772579

IRS1
Insulin receptor substrate 1

2

20

Small-scale

0.552

High

1362383

SYNP2
Synaptopodin-2

1

20

Small-scale

0.526

High

86365

B9EKJ1
Spectrin alpha chain, non-erythrocytic 1

1

20

Small-scale

0.512

High

1064160

KCMA1
Calcium-activated potassium channel subunit alpha-1

1

15

High-throughput

0.489

High

1225139

CRK
Adapter molecule crk

1

20

High-throughput

0.489

High

1423752

HOME1
Homer protein homolog 1

1

20

High-throughput

0.489

High

108851

G3X9H5
Huntingtin

1

8

High-throughput

0.479

High

470405

IL6
Interleukin-6

1

1

Small-scale

0.479

High

542884

RARA
Retinoic acid receptor alpha

1

18

Small-scale

0.479

High

653758

TTP
mRNA decay activator protein ZFP36

1

17

Small-scale

0.479

High

767029

PTN11
Tyrosine-protein phosphatase non-receptor type 11

1

3

Small-scale

0.479

High

928010

ATX1
Ataxin-1

1

16

High-throughput

0.479

High

1051204

MARK2
Serine/threonine-protein kinase MARK2

1

20

High-throughput

0.479

High

1191199

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

20

High-throughput

0.479

High

1221463

TNAP3
Tumor necrosis factor alpha-induced protein 3

1

19

Small-scale

0.479

High

1225235

TFE3
Transcription factor E3

1

20

High-throughput

0.479

High

1247181

NEB2
Neurabin-2

1

20

High-throughput

0.479

High

1282478

FACD2
Fanconi anemia group D2 protein homolog

1

12

High-throughput

0.479

High

1296280

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

20

High-throughput

0.479

High

1297829

A16L1
Autophagy-related protein 16-1

1

20

High-throughput

0.479

High

1362633

EED
Polycomb protein EED

1

20

High-throughput

0.479

High

1423564

FBX32
F-box only protein 32

1

2

High-throughput

0.479

High

1423751

ARHG7
Rho guanine nucleotide exchange factor 7

1

20

Small-scale

0.479

High

236688

B2L11
Bcl-2-like protein 11

1

1

Small-scale

0.470

High

1362880

SH3B4
SH3 domain-binding protein 4

1

14

Small-scale

0.457

High

148204

DLDH
Dihydrolipoyl dehydrogenase, mitochondrial

1

11

High-throughput

0.445

High

467770

SODC
Superoxide dismutase [Cu-Zn]

1

9

High-throughput

0.445

High

651569

CBL
E3 ubiquitin-protein ligase CBL

1

20

High-throughput

0.445

High

719288

MPIP2
M-phase inducer phosphatase 2

1

20

Small-scale

0.445

High

905952

CAV3
Caveolin-3

1

4

High-throughput

0.445

High

1222206

TSC2
Tuberin

1

20

Small-scale

0.445

High

1222708

BAD
Bcl2-associated agonist of cell death

1

9

Small-scale

0.445

High

1298226

NRIP1
Nuclear receptor-interacting protein 1

1

2

Small-scale

0.445

High

1317233

DNM1L
Dynamin-1-like protein

1

12

High-throughput

0.445

High

1408845

PARK7
Parkinson disease protein 7 homolog

1

7

High-throughput

0.445

High

1423749

TSC1
Hamartin

1

20

Small-scale

0.445

High

1362906

RIN1
Ras and Rab interactor 1

1

20

Small-scale

0.439

High

97750

E9PXB7
E3 ubiquitin-protein ligase

1

20

Small-scale

0.437

High

266813

LNX1
E3 ubiquitin-protein ligase LNX

1

20

High-throughput

0.437

High

398975

CFAD
Complement factor D

1

4

High-throughput

0.437

High

549412

ITB2
Integrin beta-2

1

4

Small-scale

0.437

High

564879

NCAM1
Neural cell adhesion molecule 1

1

8

Small-scale

0.437

High

723158

CCL5
C-C motif chemokine 5

1

1

Small-scale

0.437

High

1041417

MARK3
MAP/microtubule affinity-regulating kinase 3

1

20

High-throughput

0.437

High

1189762

PHAG1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

1

1

High-throughput

0.437

High

1221819

SC6A4
Sodium-dependent serotonin transporter

1

1

High-throughput

0.437

High

1317662

FNDC5
Fibronectin type III domain-containing protein 5

1

4

High-throughput

0.437

High

915779

HMGA2
High mobility group protein HMGI-C

1

0

High-throughput

0.426

High

1423750

NDEL1
Nuclear distribution protein nudE-like 1

1

20

Small-scale

0.417

High

1222597

SOAT1
Sterol O-acyltransferase 1

1

7

High-throughput

0.407

High

1297587

TBCD4
TBC1 domain family member 4

1

20

Small-scale

0.407

High

1298422

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

20

Small-scale

0.407

High

1317290

SDHA
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

1

10

High-throughput

0.407

High


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Last updated: 11Aug2025