HitPredict

Interactor 1: SYGP1 (F6SEU4)
Ras/Rap GTPase-activating protein SynGAP (Neuronal RasGAP) (Synaptic Ras GTPase-activating protein 1) (Synaptic Ras-GAP 1)
Gene: Syngap1

Interactor 2: ENAH (Q03173)
Protein enabled homolog (NPC-derived proline-rich protein 1) (NDPP-1)
Gene: ENAH

Species: Mus musculus

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36417873
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0017124 - SH3 domain binding GO:0045202 - synapse
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 1340 Mm			1 802
+	Mm
		100111 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		HOME1_MOUSE (1-221): 8.08e-42: 158: 21.05
+	Mm
		99957 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		EVL_MOUSE (1-372): 3.39e-30: 126: 27.08
+	Hs
		1299780 SYGP1_HUMAN (1-1340): 0: 1065: 98.59		EVL_HUMAN (1-372): 6.55e-32: 131: 27.61
+	Hs
		840556 SYGP1_HUMAN (1-1340): 0: 1065: 98.59		VASP_HUMAN (1-311): 7.93e-27: 115: 29.39
+	Mm
		100055 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		SYNJ1_MOUSE (206-589): 2.13e-09: 63.4: 14.54
+	Mm
		88450 SYGP1_MOUSE (1-1340): 0: 1075: 100.00		D3Z656_MOUSE (127-617): 5.88e-09: 61.9: 12.11
+	Hs
		1237875 SYGP1_HUMAN (1-1340): 0: 1065: 98.59		ENAH_HUMAN (497-802): 2.03e-11: 69.6: 79.51
+	Hs
		1205702 RASL3_HUMAN (169-868): 1.56e-117: 394: 34.68		HOME1_HUMAN (1-221): 5.08e-46: 170: 21.28
+	Hs
		1191428 IQGA3_HUMAN (214-734): 8.69e-110: 383: 13.64		SPRE1_HUMAN (2-278): 1.23e-48: 180: 19.61
+	Hs
		809218 IQGA1_HUMAN (219-723): 6.44e-107: 374: 13.97		VASP_HUMAN (1-311): 7.93e-27: 115: 29.39
+	Hs
		598492 NF1_HUMAN (408-712): 2.96e-82: 301: 23.21		SPRE1_HUMAN (2-278): 1.23e-48: 180: 19.61