HitPredict

Interactor 1: TRAF6 (P70196)
TNF receptor-associated factor 6 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF6) (RING-type E3 ubiquitin transferase TRAF6)
Gene: TRAF6

Interactor 2: RNF11 (Q9QYK7)
RING finger protein 11 (NEDD4 WW domain-binding protein 2) (Sid 1669)
Gene: RNF11

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	20185725, 21765415
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0008270 - zinc ion binding GO:0051865 - protein autoubiquitination GO:0061630 - ubiquitin protein ligase activity
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 530 Mm			1 154
+	Mm
		811935 TRAF2_MOUSE (38-508): 1.78e-101: 316: 25.75		RNF11_MOUSE (1-154): 3.52e-43: 141: 100.00
+	Hs
		623604 RO52_HUMAN (56-417): 2.01e-42: 159: 12.88		RNF11_HUMAN (1-154): 3.84e-43: 141: 99.35
+	Hs
		1439328 TRI39_HUMAN (61-418): 1.51e-41: 158: 12.69		RNF11_HUMAN (1-154): 3.84e-43: 141: 99.35
+	Hs
		323615 TRI37_HUMAN (56-519): 4.96e-46: 174: 14.83		RNF6_HUMAN (1-149): 1.1e-24: 100: 22.02
+	Hs
		623569 RO52_HUMAN (56-417): 2.01e-42: 159: 12.88		RNF12_HUMAN (91-146): 1.14e-21: 91.8: 39.29
+	Hs
		1348592 LNX1_HUMAN (29-183): 2.58e-11: 68.4: 22.58		RNF11_HUMAN (1-154): 3.84e-43: 141: 99.35
+	Hs
		1325769 LNX2_HUMAN (58-183): 2.7e-11: 68.4: 25.00		RNF12_HUMAN (91-146): 1.14e-21: 91.8: 39.29