Protein: TRAF2
TNF receptor-associated factor 2 (EC 2.3.2.27) (E3 ubiquitin-protein ligase TRAF2) (RING-type E3 ubiquitin transferase TRAF2)

Gene: TRAF2
Organism: Mus musculus
Interactions: 59
UniProt ID: P39429

Gene Ontology (top 5):
GO:0000151 - ubiquitin ligase complex
GO:0002637 - regulation of immunoglobulin production
GO:0002726 - positive regulation of T cell cytokine production
GO:0002947 - tumor necrosis factor receptor superfamily complex
GO:0004842 - ubiquitin-protein transferase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

148438

BIRC3
Baculoviral IAP repeat-containing protein 3

3

20

Small-scale

0.821

High

811899

UBE2N
Ubiquitin-conjugating enzyme E2 N

2

20

Small-scale

0.802

High

811866

TRAF1
TNF receptor-associated factor 1

2

18

Small-scale

0.754

High

693155

TNR5
Tumor necrosis factor receptor superfamily member 5

6

20

Small-scale

0.726

High

811909

BIRC2
Baculoviral IAP repeat-containing protein 2

2

20

Small-scale

0.726

High

669406

TNR1A
Tumor necrosis factor receptor superfamily member 1A

6

20

Small-scale

0.719

High

811905

TNAP3
Tumor necrosis factor alpha-induced protein 3

3

17

Small-scale

0.660

High

811900

TANK
TRAF family member-associated NF-kappa-B activator

3

9

Small-scale

0.636

High

811920

ITCH
E3 ubiquitin-protein ligase Itchy

2

13

Small-scale

0.621

High

811898

UB2D3
Ubiquitin-conjugating enzyme E2 D3

1

20

Small-scale

0.618

High

811906

TRAF3
TNF receptor-associated factor 3

1

19

Small-scale

0.618

High

811897

TNR3
Tumor necrosis factor receptor superfamily member 3

2

20

Small-scale

0.606

High

811903

TAXB1
Tax1-binding protein 1 homolog

2

20

Small-scale

0.601

High

811908

M3K7
Mitogen-activated protein kinase kinase kinase 7

2

19

Small-scale

0.601

High

811893

TRAF2
TNF receptor-associated factor 2

1

17

High-throughput

0.590

High

811896

TNR4
Tumor necrosis factor receptor superfamily member 4

2

20

Small-scale

0.586

High

312476

NEMO
NF-kappa-B essential modulator

2

14

Small-scale

0.584

High

811894

CD27
CD27 antigen

2

20

Small-scale

0.584

High

811925

SHRPN
Sharpin

2

6

Small-scale

0.576

High

811933

RBCC1
RB1-inducible coiled-coil protein 1

1

20

Small-scale

0.561

High

811907

RIPK1
Receptor-interacting serine/threonine-protein kinase 1

1

20

Small-scale

0.536

High

811935

RNF11
RING finger protein 11

1

7

Small-scale

0.515

High

204645

TNR11
Tumor necrosis factor receptor superfamily member 11A

1

20

Small-scale

0.506

High

204223

M3K5
Mitogen-activated protein kinase kinase kinase 5

1

20

Small-scale

0.501

High

811937

TBK1
Serine/threonine-protein kinase TBK1

1

20

Small-scale

0.501

High

811934

TR13B
Tumor necrosis factor receptor superfamily member 13B

1

8

Small-scale

0.489

High

811915

TIFA
TRAF-interacting protein with FHA domain-containing protein A

1

5

Small-scale

0.481

High

107136

F8VQ72
Mitogen-activated protein kinase kinase kinase 1

1

19

Small-scale

0.479

High

266981

FHL2
Four and a half LIM domains protein 2

1

18

Small-scale

0.479

High

483859

CSF1R
Macrophage colony-stimulating factor 1 receptor

1

4

Small-scale

0.479

High

599238

IL7RA
Interleukin-7 receptor subunit alpha

1

1

Small-scale

0.479

High

714569

CASP2
Caspase-2

1

20

Small-scale

0.479

High

811895

NEDD4
E3 ubiquitin-protein ligase NEDD4

1

13

Small-scale

0.479

High

811901

CREB1
Cyclic AMP-responsive element-binding protein 1

1

6

Small-scale

0.479

High

811902

TRAD1
TRAF-type zinc finger domain-containing protein 1

1

9

Small-scale

0.479

High

811910

IRAK1
Interleukin-1 receptor-associated kinase 1

1

12

Small-scale

0.479

High

811911

MABP1
Mitogen-activated protein kinase-binding protein 1

1

6

Small-scale

0.479

High

811914

RIGI
Antiviral innate immune response receptor RIG-I

1

20

High-throughput

0.479

High

811917

M3K11
Mitogen-activated protein kinase kinase kinase 11

1

7

Small-scale

0.479

High

811918

M4K5
Mitogen-activated protein kinase kinase kinase kinase 5

1

20

Small-scale

0.479

High

811923

MAVS
Mitochondrial antiviral-signaling protein

1

16

Small-scale

0.479

High

811924

TRAIP
E3 ubiquitin-protein ligase TRAIP

1

20

Small-scale

0.479

High

811930

TAB2
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2

1

18

Small-scale

0.479

High

811931

TR13C
Tumor necrosis factor receptor superfamily member 13C

1

5

Small-scale

0.479

High

811936

M3K14
Mitogen-activated protein kinase kinase kinase 14

1

20

Small-scale

0.479

High

630392

TNR9
Tumor necrosis factor receptor superfamily member 9

1

20

Small-scale

0.457

High

811912

ZMIZ1
Zinc finger MIZ domain-containing protein 1

1

12

High-throughput

0.457

High

811916

TNR14
Tumor necrosis factor receptor superfamily member 14

1

20

Small-scale

0.457

High

811921

MKNK2
MAP kinase-interacting serine/threonine-protein kinase 2

1

12

High-throughput

0.457

High

811926

LZTS2
Leucine zipper putative tumor suppressor 2

1

20

High-throughput

0.457

High

811927

FCRLA
Fc receptor-like A

1

6

High-throughput

0.457

High

811928

COG2
Conserved oligomeric Golgi complex subunit 2

1

2

High-throughput

0.457

High

811922

CIKS
E3 ubiquitin ligase TRAF3IP2

1

12

Small-scale

0.445

High

811929

CDK9
Cyclin-dependent kinase 9

1

5

Small-scale

0.439

High

811904

SLMAP
Sarcolemmal membrane-associated protein

1

17

High-throughput

0.417

High

811913

NUP98
Nuclear pore complex protein Nup98-Nup96

1

6

High-throughput

0.417

High

811919

BRI3B
BRI3-binding protein

1

1

High-throughput

0.417

High

811932

IKIP
Inhibitor of nuclear factor kappa-B kinase-interacting protein

1

1

High-throughput

0.417

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025