Protein: SCML2
Sex comb on midleg-like protein 2

Gene: SCML2
Organism: Homo sapiens
Interactions: 69
UniProt ID: Q9UQR0

Gene Ontology (top 5):
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0009653 - anatomical structure morphogenesis
GO:0031519 - PcG protein complex
GO:0042393 - histone binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1138561

SMBT2
Scm-like with four MBT domains protein 2

2

19

High-throughput

0.783

High

1220905

PHC2
Polyhomeotic-like protein 2

2

19

Small-scale

0.754

High

1273974

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

6

3

Small-scale

0.738

High

1304185

RING2
E3 ubiquitin-protein ligase RING2

5

20

Small-scale

0.709

High

1252554

LNX1
E3 ubiquitin-protein ligase LNX

2

2

High-throughput

0.700

High

625646

CDK2
Cyclin-dependent kinase 2

1

1

Small-scale

0.691

High

1292160

SCMH1
Polycomb protein SCMH1

1

19

High-throughput

0.691

High

415111

CDK1
Cyclin-dependent kinase 1

1

1

Small-scale

0.646

High

941589

RNF4
E3 ubiquitin-protein ligase RNF4

2

2

High-throughput

0.606

High

918153

H4
Histone H4

2

11

High-throughput

0.584

High

370735

ESR1
Estrogen receptor

2

12

High-throughput

0.571

High

209190

NCK2
Cytoplasmic protein NCK2

2

6

High-throughput

0.553

High

71280

HNRC2
Heterogeneous nuclear ribonucleoprotein C-like 2

1

3

High-throughput

0.536

High

380883

S100B
Protein S100-B

1

4

High-throughput

0.536

High

1087492

H2B2E
Histone H2B type 2-E

1

15

High-throughput

0.536

High

1335794

CBX8
Chromobox protein homolog 8

1

20

High-throughput

0.536

High

758369

CDN1A
Cyclin-dependent kinase inhibitor 1

1

1

Small-scale

0.516

High

217964

PRKY
Putative serine/threonine-protein kinase PRKY

1

1

High-throughput

0.514

High

48886

POTB3
POTE ankyrin domain family member B3

2

1

High-throughput

0.504

High

331649

CCNE2
G1/S-specific cyclin-E2

1

1

Small-scale

0.500

High

804157

CDN1B
Cyclin-dependent kinase inhibitor 1B

1

1

Small-scale

0.500

High

608887

SPR1B
Cornifin-B

1

1

High-throughput

0.489

High

1164322

POTEG
POTE ankyrin domain family member G

1

1

High-throughput

0.489

High

1302195

TCPQM
T-complex protein 1 subunit theta-like 2

1

6

High-throughput

0.489

High

123346

CBX4
E3 SUMO-protein ligase CBX4

1

20

Small-scale

0.479

High

331906

NSD2
Histone-lysine N-methyltransferase NSD2

1

10

Small-scale

0.479

High

360548

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

2

High-throughput

0.479

High

391973

H2A1B
Histone H2A type 1-B/E

1

5

High-throughput

0.479

High

487851

ANDR
Androgen receptor

1

12

High-throughput

0.479

High

554077

RFA2
Replication protein A 32 kDa subunit

1

2

High-throughput

0.479

High

652629

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

2

High-throughput

0.479

High

707795

H2B1B
Histone H2B type 1-B

1

15

High-throughput

0.479

High

718330

BMI1
Polycomb complex protein BMI-1

1

20

Small-scale

0.479

High

780340

CCNF
Cyclin-F

1

2

High-throughput

0.479

High

809034

YAP1
Transcriptional coactivator YAP1

1

6

High-throughput

0.479

High

847117

SMCA4
Transcription activator BRG1

1

5

Small-scale

0.479

High

918775

H2B1C
Histone H2B type 1-C/E/F/G/I

1

15

High-throughput

0.479

High

935383

H31
Histone H3.1

1

20

High-throughput

0.479

High

944993

RED1
Double-stranded RNA-specific editase 1

1

1

High-throughput

0.479

High

952706

H33
Histone H3.3

1

20

High-throughput

0.479

High

968012

PO5F1
POU domain, class 5, transcription factor 1

1

6

High-throughput

0.479

High

1027335

CBX3
Chromobox protein homolog 3

1

20

High-throughput

0.479

High

1059204

CBX2
Chromobox protein homolog 2

1

20

Small-scale

0.479

High

1067201

BRD3
Bromodomain-containing protein 3

1

12

High-throughput

0.479

High

1189056

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

1

High-throughput

0.479

High

1200767

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.479

High

1221844

SMC5
Structural maintenance of chromosomes protein 5

1

4

High-throughput

0.479

High

1304837

TBX5
T-box transcription factor TBX5

1

5

High-throughput

0.479

High

1326789

WWTR1
WW domain-containing transcription regulator protein 1

1

2

High-throughput

0.479

High

46511

A0A286YEY3
SLIT-ROBO Rho GTPase activating protein 2B

1

2

High-throughput

0.470

High

524093

XRCC6
X-ray repair cross-complementing protein 6

1

0

High-throughput

0.458

High

653033

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

1017262

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

1

0

Small-scale

0.458

High

316204

CBX6
Chromobox protein homolog 6

1

20

High-throughput

0.445

High

483673

SRG2B
SLIT-ROBO Rho GTPase-activating protein 2B

1

2

High-throughput

0.439

High

323323

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

1

High-throughput

0.437

High

721802

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.437

High

1162141

RHDF2
Inactive rhomboid protein 2

1

1

High-throughput

0.437

High

1256081

RHBL4
Rhomboid-related protein 4

1

1

High-throughput

0.437

High

1331651

PKHA4
Pleckstrin homology domain-containing family A member 4

1

3

High-throughput

0.437

High

1350505

HECW2
E3 ubiquitin-protein ligase HECW2

1

4

High-throughput

0.437

High

1334466

CB39L
Calcium-binding protein 39-like

2

0

High-throughput

0.316

High

345152

CYTA
Cystatin-A

1

0

High-throughput

0.279

Low

574478

RL35A
Large ribosomal subunit protein eL33

1

0

High-throughput

0.279

Low

611365

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

0

High-throughput

0.279

Low

714780

TRY3
Trypsin-3

1

0

High-throughput

0.279

Low

373446

CATA
Catalase

1

0

High-throughput

0.249

Low

423396

PDIA1
Protein disulfide-isomerase

1

0

High-throughput

0.249

Low

1330194

TXNIP
Thioredoxin-interacting protein

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024